Bøger af Minakshi Rathod

Osnownoj cel'ü dannogo issledowaniq qwlqetsq prigotowlenie lekarstwennyh ledencow dlq udobnogo wwedeniq dozy ambroxola HCL pediatricheskim pacientam. Jeti pacienty imeüt disfagiü, dlq takih pacientow udobny takie dozirowki. Jeti ledency okazywaüt mukoliticheskoe i mukokineticheskoe dejstwie. Razlichnye polimery, takie kak HPMC k100m, HPMC k4m, SCMC ispol'zuütsq dlq prodleniq wyswobozhdeniq lekarstwa do 30 minut. Takim obrazom, äkonomichnye ledency s medlennym wyswobozhdeniem ambroxola HCL w polosti rta qwlqütsq bezopasnoj i äffektiwnoj lekarstwennoj formoj dlq pediatrii i obladaüt luchshej biodostupnost'ü. Oblast' primeneniq dannogo issledowaniq: issledowanie in-vivo, korrelqciq in-vivo in-vitro, razrabotka razlichnyh receptur s ispol'zowaniem razlichnyh polimerow, kotorye prodlewaüt wyswobozhdenie lekarstwa, razrabotka razlichnyh receptur, soderzhaschih kombinaciü lekarstw, razrabotka receptur dlq lecheniq razlichnyh problem w pediatrii. Ledency qwlqütsq udobnoj formoj dozirowki dlq detej. Bol'shinstwo formul ambroxola HCL dostupny, no, razrabatywaq formulu, my mozhem uluchshit' stabil'nost' formuly, fixirowannuü dozirowku, powysit' komplaentnost' pacientow i biodostupnost' preparata.

The main aim of this study is prepared medicated lollipops is easy to give the dose of ambroxol HCL to pediatric patients. Those patients have an dysphagia, for these type of patients are comfortable with these dosages from. These lollipops gives mucolytic and mucokinetic action. The various polymers such as HPMC k100m, HPMC k4m, SCMC are used for extended the release of drug up to 30 min. Thus cost effective and slow release medicated lollipops of ambroxol HCL in oral cavity is a safe and effective dosage form for pediatrics and having better bioavailability. The scope of this study is In-vivo study, In-vivo in-vitro correlation,Formulating various formulation using different polymers those extended the drug release, Formulating various formulation containing combination of drugs are used, Formulating this formulation for the treatment of various problems in pediatrics. The lollipops are liking dosages form for children's. Most of the ambroxol HCL formulations are available, but by developing formulation we can improve stability of formulation, fixed dosing, increase patient compliance & also bioavailability of drug.