Bøger af Smita Bedis

Changes in surfactant 17R4 concentration influenced the physio-chemical characteristics of an oil- in-water emulsion the most.From the study, we can conclude that the physcio-chemical properties of an oil-in-water emulsion were mostly affected by the variations in the contents of surfactant 17R4 A and NaCl. The NaCl-surfactant-oil interactions had a strong influence on the stability of the prepared emulsion. Pluronic surfactant 17R4 when used in minimal amount (1%) alongside Ludox and 2mg NaCl resulted to the most stable emulsion which stood on the bench beyond 6months without any sign of creaming. Oil-in-water emulsion wastes may be effectively treated using the electrochemical destabilization method. The aluminum provided and the bulk pH are the two most critical factors in the process. Experiments with a steady-state pH outside of the 5¿9 range result in no emulsion break-up and, as a result, no COD elimination. In addition, the electrolyte has a significant impact on the outcomes. According to our second scheme, we found that nanoemulsion has the potentially help for enhancing the oral bioavailability of ibuprofen.

Pramipexole hydrochloride (PPX) and ropinirole hydrochloride (RPN), are nonergot dopamine agonist, selective for dopamine D2 and D3 receptors, in contrast to ergot derivatives that also have activity at D1 type and other nondopaminergic neurotransmitter receptors, indicated for the treatment of the signs and symptoms of Parkinson's disease. The nigrostristrial neurodegeneration that proceeds over the cource of parkinson¿s disease limits the no. of striatal nerve terminals that are available to decarboxylate levodopa to dopamine. Drugs (PPX and RPN) that act directly to stimulate dopamine receptors, however do not require functioning dopaminergic nerve terminals and can be useful in the management of last- stage disease problems during levodopa therapy. The present work deals with development of validated analytical methods for these antiparkinson¿s agents in bulk and in their respective pharmaceutical dosage forms by RP-HPLC and HPTLC techniques and different UV spectrophotometric methods.