Bøger af Sumit Kumar

O tipo mais prevalente de demência senil, a doença de Alzheimer (DA), afecta 10% das pessoas com mais de 65 anos e mais de 50% das pessoas com mais de 85 anos. Nos próximos 50 anos, prevê-se que o número de americanos com DA aumente de 4,5 milhões para 13,2 milhões, segundo as estimativas actuais. Embora a investigação fundamental sobre a doença de Alzheimer tenha avançado significativamente nos últimos 20 anos, não existe atualmente nenhum tratamento que possa parar, inverter ou mesmo atrasar o inevitável processo neurodegenerativo. Em vez disso, os medicamentos atualmente disponíveis apenas podem aliviar temporariamente os sintomas cognitivos. Existem vários elementos diferentes relacionados com a fisiopatologia da doença de Alzheimer. A doença de Alzheimer (DA) pré-clínica é um termo que só recentemente foi utilizado para descrever uma doença que tem um biomarcador fisiopatológico presente, caraterístico da DA, na ausência de sintomas clínicos específicos.

The most prevalent type of senile dementia, Alzheimer's disease (AD), affects 10% of people over 65 and over 50% of people over 85. In the next 50 years, it is expected that the number of Americans with AD will rise to 13.2 million from the current estimate of 4.5 million. Although basic research into AD has advanced significantly over the past 20 years, there is currently no treatment that can stop, reverse, or even delay the unavoidable neurodegenerative process. Instead, currently available medications can only temporarily alleviate cognitive symptoms. There are several different elements connected to the pathophysiology of AD. Preclinical Alzheimer's disease (AD) is a term that has only recently been used to describe an illness that has a pathophysiological biomarker present which characteristic for AD in the absence of specific clinical symptoms.

Cosmic Harmony: The Eternal Symphony" is an enthralling sci-fi fantasy that weaves together the grandeur of the cosmos and the enchanting allure of Indian mythology. Follow Raj and Ria, the Mythic Protectors, on an extraordinary journey filled with cosmic battles, heroic quests, and a love that transcends galaxies. With mesmerizing imagery and a captivating narrative, this tale invites readers to explore a universe of wonder, harmony, and the eternal power of love. Get ready to be swept away into a symphony of adventure and cosmic beauty that will leave you spellbound until the very last page.

One of the leading causes of blindness, Glaucoma is multifactorial in origin. At a systemic level, hypertension, hypotension leading to reduced ocular blood flow, vascular dysregulation, oxidative stress and cardiovascular history are associated with glaucoma. Glaucoma therapeutics are based on manipulation of the Autonomic Nervous System in the anterior segment of the eye.On the other hand, dissimilarities in the risk factors concerned with high tension glaucoma and normal tension glaucoma suggest that these two forms of glaucoma could be taken as separate entities, each with their own pathophysiology, yet the relationship between the two is not convincing.Based on research and comparative analyses so far in India, the first ever compendium 'Glaucoma - the autonomic perspective' gives us an insight to the autonomic dysregulation in glaucoma, thus enhancing the bright scope of this topic in future for the medical researchers.

Traumatic Brain Injury (TBI) affects a huge proportion of the population worldwide and it is more widely recognized as a significant health issue characterized by a wide spectrum of pathological symptoms followed by long-term disability. The various post-injury acute and chronic mechanisms may contribute to neurodegeneration. Patients with a history of TBI are more likely to develop proteinopathy, which is a pathological hallmark of neurodegenerative diseases. This book mainly focuses on the epidemiology, Pathophysiology, animal model that are linked to TBI.A window for therapeutic interventions is provided by the secondary brain injuries that follow the first brain insult, which results in the parenchyma suffering immediate, severe, and permanent damage. As of now, degeneration of axons, oxidative stress, oxidative stress mitochondrial malfunction, excitotoxicity and apoptotic cell death of neurons and glia are hallmark phenomena after delayed secondary CNS injury. Despite the fact that each TBI case is unique and that affected people show varying levels of damage, varying localised injury patterns, and profile of recovery differing.

Lo Shu Grid is Chinese Life Prediction Method. This book can assist in learning this method. The book covers the basics of Lo Shu grid essential to understand the advance part in numerology. The book also covers the predictions in the area of marriage, marriage success/failure, Career, Finance , Stock Market , Career Fields, financial success etc. Case Study of prominent personalities are also included to make the understanding simple. At the end, the remedies related to it are provided in detail.

There is always need of some better materials, Processes and Techniques. The alluminium having light weight is most commonly used material now days.The alluminium alloy AA6063 has been welded using pulsed GTAW. The Process is optimised for good weld bead geometry. The welded material is Tested in lab for its strength. The work presents an approach based on design of experiments for the determination of optimum welding parameters for a good weld bead.

"Kuchh to kahoon" written by Sumit Kumar is treat to read, it's full of motivation. I found this book a worth reading and will advice readers to go for this book. It's language touches me and the content is of very high quality."-- Wasim Akram Asstt. Professor

Broken Memories is a summary of the life woven into love and Ruswai. In which there is a dream, there is a picture, there is Iltza, there is light, it is relaxed and there is defeat. This book will introduce you to your past and tomorrow. Will teach the love of love, Will teach you to love Will teach you to fall in love. And will teach us to overcome love.

The authors address and identify the extent of poverty in Afghanistan over the years, the spatial patterns and regional imbalances of poverty in Afghanistan, the distinguishing characteristics of the poor in Afghanistan, and explore shocks faced by the poor in Afghanistan as well as subsequent coping strategies.