Bøger af Walaa H Mahmoud

Two new Schiff bases were prepared. The formed Schiff bases ligands were further employed for the synthesis of new complexes through reaction with Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) , Cd(II), La(III), Er(III) and Yb(III) metal ions. The synthesized Schiff bases and their metal complexes were characterized using some physicochemical techniques including elemental analysis, FT-IR, UV¿Vis, conductimetric measurement, magnetic susceptibility, mass spectrometry as well as thermal analyses (TG/DTG). The Schiff bases and their chelates have been screened for their antimicrobial activity and anticancer activity.

Two different Schiff bases were prepared by condensation between isatin drug and diaminopyridine or isoleucine amino acid and characterized using different physio-chemical techniques. The prepared ligands were used for synthesizing different transition metal complexes. The prepared metal complexes were identified using different tools like FT-IR, Mass, SEM, XRD, elemental analysis , 1HNMR, etc. Also screening its aantimicrobial activity and anticancer activity were done. The data confirmed the high activity of the ligands and their chelates.

Four novel Nano Schiff bases and their nano transition complexes with Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) were prepared and subjected to many analytical techniques such as elemental analyses, mass spectroscopy, SEM, XRD, IR, 1H NMR, molar conductance, thermal analyses techniques (TG and DTG). The chelates were found to have nano sized ranged from 17 to 21 nm. Some biological applications were screened for the prepared nano compounds in addition to screening their toxicity on the normal human cells.