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The extraction of the essential oil from the peels of Citrus x sp was performed using the hydrodistillation technique and its chemical constituents were characterized by Gas (GC-MS). The total phenolic content (CFT) was quantified and the total flavonoid content (CFLT).The physical-chemical parameters of refractive index .The nanoemulsions were formulated .the anti-inflammatory method of protein denaturation, antioxidant capacity by the spectrophotometric and antiarthritic potentialby the BSA-induced .Through GC-MS it was possible to identify ten (10) constituents present in the essential oil of Citrus sp, with limonene being the major component (70.25%) For CFT and CFLT, 227.645 mg L-1 and the refractive index was and 86.57 mg L-1 were quantified, respectively, and the refractive index was quantified 1.475 For the results of the antioxidant capacity, the nanoemulsions presentand 86.57 mg L-1 were quantified,For anti-arthritic activity,it is noted that among the nine (9) synergies formulated, S1, S6 and S8,antioxidant capacity, the nanoemulsions the best EC50 result of 9.10 for NOE3,In anti-inflammatory activitysynergies S4, amounted to 4.63mg L-1.
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