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Frontiers in Clinical Drug Research - Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research - Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The second volume of this series features 5 chapters that cover a variety of topics including: -Chronic myeloid leukemia -Bispecific and multivalent antibodies -Natural Killer cells therapy for bone marrow transplantation -Nanoparticles in health and disease -Monoclonal antibody therapy for lymphoma
Frontiers in Clinical Drug Research - Central Nervous System presents the latest researches and clinical studies on the central nervous system (CNS). It covers a range of topics such as the development and pathophysiology of the brain and spinal cord, physiological sites of drug action in the CNS and clinical findings on drugs used to treat CNS defects due to injury or impaired development. In addition to clinical research on humans, the book also highlights other avenues of CNS medicine and research such as pain medicine, stem cell research, pharmacology, toxicology and translational models in animals. The second volume of the series features chapters on the following topics: - Nucleic acids as drugs for neurodegenerative diseases - Cellular Cysteine Network (CYSTEINET): - Non-motor Symptoms in Parkinson's Disease and drug therapies - Multi-modal pharmacological treatments for major depressive disorder
Interest Rate Modeling for Risk Management addresses interest rate modeling for risk management. The interest rate model is specified under the real-world measure, and the result is used as to generate scenarios for interest rates. This type of system is referred to as 'real-world model' in this book. The book introduces a theoretical framework that allows estimating the market price of interest rate risk. For this, the book starts with a brief explanation of stochastic analysis, and introduces interest rate models such as Heath-Jarrow-Morton, Hull-White and LIBOR models. The real-world model is then introduced in subsequent chapters. Additionally, the book also explains some properties of the real-world model, along with the negative price tendency of the market price for risk and a positive market price of risk (with an example of this actually occurring). Readers will also find a handy appendix with proofs to complement the numerical methods explained in the book. This book is intended as a primer for practitioners in financial institutions involved in interest rate risk management. It also presents a new perspective for researchers and graduates in econometrics and finance on the study of interest rate models.
Serial Killers Around the World: The Global Dimensions of Serial Murder compiles serial murder case studies from several countries - from Australia to Great Britain, and from Japan to Pakistan. The author has covered accounts on a wide array of serial killers including some well known felons namely Jack the Ripper, The Butcher of Mons, Martin & Marie Dumollard, as well as some of the lesser known serial slayers such as Daisy DeMelker, Yoshio Kodaira, Javed Iqbal and many more. The book highlights six dimensions of each case: the killer(s), the serial murders, other crimes, communication, the investigation and trial and punishment of the accused. Readers, both general and aspiring criminologists alike, will find Serial Killers Around the World an interesting resource for critical information on serial murders committed in nations around the world.
The aim of this book series is to publish high quality economic research in agricultural and applied economics. It particularly fosters quantitative studies which make original contribution on important economic issues, the results of which help to understand and solve real economic problems. This volume contains research papers focusing on the areas of agricultural policy, agricultural price volatility, agricultural finance and cooperatives, consumption economics, firm production and organization, human capital convergence, international economics and multinational business, investment decisions in organic agriculture, market structure and industry studies. The research papers of this volume make use of recent methodological approaches and provide conclusions which are useful to both private sector participants and policy-makers.
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