Bøger udgivet af Elsevier Science & Technology

Adverse Childhood Experiences and Their Life-Long Impact explores how these experiences influence cognitive, behavioral and social experiences in adulthood. The book conceptualizes the types of violence, abuse, neglect, and/or trauma that factor into ACEs. It also explores the psychopathological outcomes of ACEs among children, including neurodevelopmental and psychosocial mechanisms. By drawing on cross-cultural perspectives, the authors provide insight into the variations between the adversity and trauma children experience. Sections also cover preventive measures, risk factors and various forms of interventional treatment, making this book a core read for psychologists, physicians, social workers, educators and researchers in the field.

The Marketing of Academic, National and Public Libraries Worldwide: Marketing, Branding, Community Engagement enables readers to learn about the most up-to-date trends, as well as hands-on practices and marketing tactics taken directly from 48 highly seasoned marketing and community engagement librarians around the world, namely in Africa, Australia, Canada, Croatia, Germany, Hong Kong, Latvia and Qatar. Via a series of in-depth and semi-structured interviews, this book provides insights into successful marketing strategies librarians can use to encourage donors and patrons to understand that their libraries are a great choice for fulfilling information needs, recreational interests, intellectual pursuits, and more.

Bioactive Lipid Mediators in Cardiopulmonary Pharmacology, Volume 97 updates readers on topics surrounding Bioactive lipid mediators. These mediators are involved in a vast array of signaling pathways that regulate both physiological and pathophysiological responses. Chapters in this new release include Cyclooxygenases and Vascular Function, Cyclooxygenases and Platelet Function, Eicosanoids and Cardiomyopathies, Cytochrome P450 Bioactive Lipids in the Heart, Epoxide Hydrolase and Leukotoxin in the Heart and Lung, Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response, Bioactive Lipids in Hypertension, Cytochrome P450 Metabolites and Angiogenesis, 20-Hydroxyeicosatetraenoic Acid and Vascular Function, and more. Other critical sections cover Cytochrome P450 Eicosanoids and the Brain, Omega-3 Oxylipids, Resolvins, Lipoxins and Inflammation, Endocannabinoids as Bioactive Metabolites, and Oxylipins and Aspirin Exacerbated Respiratory Disease.

Pharmaceutics: Basic Principles and Application to Pharmacy Practice, Second Edition is a valuable textbook covering the role and application of pharmaceutics within pharmacy practice. This updated resource is geared toward meeting and incorporating the current curricular guidelines on pharmaceutics and laboratory skills mandated by the American Council for Pharmacy Education. It includes a number of student-friendly features, including chapter objectives and summaries, practical examples, case studies, numerous images and key-concept text boxes. Two new chapters are included, as well as a new end of chapter section covering "critical reflections and practice applications". Divided into three sections - Physical Principles and Properties of Pharmaceutics; Practical Aspects of Pharmaceutics; and Biological Applications of Pharmaceutics - this new edition covers all aspects of pharmaceutics and providing a single and compelling source for students.

Project Finance in Theory and Practice: Designing, Structuring, and Financing Private and Public Projects, Fourth Edition provides essential, core coverage of project finance, offering new insights into Sharia-compliant instruments and a comprehensive overview of the current state of international regulation of banking post financial crisis. This updated edition includes new case studies and topics related to country risk, along with insights from project finance experts who share their specialized knowledge on legal issues and the role of advisors in project finance details. The book will be useful for readers at all levels of education and experience who want to learn how to succeed in project finance.

Mechanisms of Morphogenesis, Third Edition offers a bottom-up discussion of mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. Across foundational, applied and methods-based chapters, this book examines molecular nano-machines cooperation, generate cell shape, direct cell migration, and shape, form and rates of growth of various tissues in the body. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and likely future developments, along with strategies to apply basic morphogenesis science across ever evolving applications. Newly added chapters feature case-study-driven discussions of morphogenesis in natural embryos and organoids, and illustrate how pathological morphogenesis can generate variants of body form. This edition has also been updated with analysis of large-scale and scale-invariant mechanisms, for example, morphogenesis by differential growth in mechanically connected tissues.

Essentials of Ultrasound Imaging is an introduction to all aspects of acquiring and measuring pulse-echo data to form images. The book provides in-depth exploration of key physical processes, including wave propagation and interaction with physical media, piezoelectric transducers, arrays, and beam formation, and concludes with a survey of advanced topics in ultrasound. Uniquely, principles are revealed by examples from software simulation programs designed to demonstrate ultrasound concepts, and image and signal processing. There are also numerous examples from a Verasonics Vantage Research Ultrasound System to provide unparalleled insight into each step of ultrasound image creation, including signal processing, transducer operation, different types of beamforming, and image formation. The content is organized around a central functional block diagram which is, in turn, related to physical processes and processing involved in clinical and research imaging systems. With a thorough grounding in the fundamentals of physics and methods of ultrasound imaging, readers can better appreciate the introduction of advanced topics and various applications of ultrasound.

Advanced Frequency Regulation Strategies in Renewable-Dominated Modern Power Systems discusses advanced control strategies positioned to attain stable and reliable electric power operation in highly renewable modern grids. These strategies are increasingly valuable components of the practitioner technical toolbox, and are essential to maintain frequency and voltage regulations, assert power quality standards, and ensure overall grid stability. This book focuses on the rapid integration of renewable-based generating units in power systems, highlighting state-of-the-art technologies and emerging topics pertaining to load frequency control, robust control strategies, and energy storage systems. Chapters are accompanied by case studies drawn from modern international practice.

DNA Interactions With Drugs and Other Small Ligands: Single Molecule Approaches and Techniques provides the reader with all the main information, a "state-of-the-art" of sorts and an overall review of the field. There is no other book currently available that covers all these subjects together. On the contrary, the different subjects that are developed in this book are currently scattered in journal articles and other books.

Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers, and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics. Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure.

Artificial Intelligence, Machine Learning, and Deep Learning in Precision Medicine and Liver Diseases: Concept, Technology, Application, and Perspectives combines four major applications of artificial intelligence (AI) within the field of clinical medicine specific to liver diseases: radiology imaging, electronic health records, pathology, and multiomics. The book provides a state-of-the-art summary of AI in precision medicine in hepatology, clarifying the concept and technology of AI and pointing to the current and future applications of AI within the field of hepatology. Coverage includes data preparation, methodology and application within disease-specific cases in fibrosis, viral and steatohepatitis, cirrhosis, hepatocellular carcinoma, acute liver failure, liver transplantation, and more. The ethical and legal issues of AI and future challenges and perspectives are also discussed. By highlighting many new AI applications which can further research, diagnosis, and treatment, this reference is the perfect resource for both practicing hepatologists and researchers focused on AI applications in medicine.

Clinician's Guide to Sexuality and Autism: A Guide to Sex Education for Individuals with Autism Spectrum Disorders is the first book to provide clinicians with comprehensive curriculum of sexuality education skills for people with Autism Spectrum Disorders (ASD). Starting with the importance of teaching sexuality skills to people with autism, this book provides an outline and overview of the recommended teaching strategies (e.g., Behavioral Skills Training, Cool vs. Not Cool, video modeling). This book also reviews the fourteen skill domains directly related to sexuality, including the key skills one should acquire in each domain. A timeline focusing on what skills should be targeted at what age and what skills to teach across the lifespan are also discussed. The curriculum covers domains that are often neglected in sex education for people with different disabilities in general (e.g. values, types of relationships, gender identity, or preferences). Additionally, this curriculum addresses component skills of sexuality in a way that allows early teaching to build upon areas of learning systematically over time, thus likely to have an improvement in teaching over time.

Mesenchymal Stem Cells: Biological Concepts, Current Advances, Opportunities and Challenges systematically summarizes and discusses the basic concepts and latest updates of mesenchymal stem cells (MSCs) in the past 60 years, as well as the latest progress of clinical translational research and regulatory policy at home and abroad, which will be of great practical significance for promoting and guiding the future development of stem cell production and regenerative medicine.

Translational Radiation Oncology covers the principles of evidence-based medicine and applies them to the design of translational research. The book provides valuable discussions on the critical appraisal of published studies and recent developments in radiation oncology, allowing readers to learn how to evaluate the quality of such studies with respect to measuring outcomes and make effective use of all types of evidence. By reading this book, researchers have access to a practical approach to help them navigate challenging considerations in study design and implementation. It is a valuable resource for researchers, oncologists and members of biomedical field who want to understand more about translational research applied to the field of radiation oncology. Translational medicine serves as an indispensable tool in grant writing and funding efforts, so understanding how to apply its principles to research is necessary to guarantee that results will be impactful to patients.

Digital Teaching, Learning and Assessment: The Way Forward is the result of the continuous discussion taking place in the teaching and learning space of what the future holds for academics and their stakeholders, post pandemic students. The editors of this book work in the teaching and learning domain and consider such discussion critical to ensure that students of the future are well serviced by all concerned. The book brings such discussions to one platform where academics, administrators and other stakeholders like researchers and regulatory bodies ponder ideas and practices and how the digital world will dominate and change the teaching/learning space.

The Nuts and Bolts of Proofs: An Introduction to Mathematical Proofs, Fifth Edition provides basic logic of mathematical proofs and how they work. The book offers techniques for both reading and writing proofs, discusses techniques in proving if/then statements by contrapositive and proofing by contradiction, includes the negation statement, and/or, examines various theorems, such as the if and only-if, equivalence theorems, existence theorems, and the uniqueness theorems. In addition, the use of counter examples, mathematical induction, composite statements including multiple hypothesis and multiple conclusions, and equality of numbers are also covered. The book also provides mathematical topics for practicing proof techniques. Included here are the Cartesian products, indexed families, functions, and relations. The last chapter of the book provides review exercises on various topics. Undergraduate students in engineering and physical science will find this book accessible as well as invaluable.

The Handbook of the Economics of Education describes the research frontier in key topical areas and sets the agenda for further work. Modern analysis in the economics of education has made tremendous strides in understanding fundamental issues related to the production of human capital and the impact of varying institutional features of education systems. By bringing together some of the world¿s leading scholars, this volume provides a unique view of scholarship in the area. The international perspectives of the editors ¿ Hanushek at Stanford, Machin at LSE, and Woessmann at Munich ¿ leads to a volume with something for all researchers. Topics range from the economics of early childhood education to inequality in society to cash transfers in developing countries.