Bøger udgivet af Springer Verlag, Japan

This book covers the most up-to-date photoaffinity labeling method to tackle the key loop module involved in the binding process of a bioactive small molecule to its host protein.

The objective of the book is to introduce researchers and graduate course students who are interested in "photon-working switches" not only to the fundamentals but also to the latest research being carried out in this field.

The main objective of this book is to integrate environmental knowledge observed in local agriculture, based on the understanding of soils science and ecology, and to propose possible technical solutions and a more integrated approach to tropical agriculture.

Parts 5 and 6, "Safety Assessment of Topically Applied Compounds" and "Experimental Methods of Skin Permeation", respectively, show safety issues and experimental methods for topical formulations. The final part consists of comments on therapeutic and cosmetic formulations by medical doctors and pharmacists.

Precise targeting such as image-guided RT and active breathing control are now capable of treating lymphoma lesions that shift with respiration or peristalsis. This book, serving as a guide, provides the necessary knowledge for radiation oncology, practice, and planning involving the RT techniques of treating extranodal lymphomas.

This book is a compilation of selected papers from the 4th ENRI International Workshop on ATM/CNS (EIWAC2015). The work focuses on novel techniques for aviation infrastructure in air traffic management (ATM) and communications, navigation, surveillance, and informatics (CNSI) domains.

This is the first textbook to focus on Aortopathy, a new clinical concept for a form of vasculopathy. The first section of the book starts from discussing general concept and history of Aortopathy, and then deals with its pathophysiology, manifestation, intrinsic factor, clinical implication, management and prevention. The second part closely looks at various disorders of the Aortopathy such as bicuspid aortic valve and coarctation of aorta. The book editors have published a lot of works on the topic and have been collecting relating data in the field of congenital heart disease for the past 20 years, thus present the book with confidence. The topic - an association of aortic pathophysiological abnormality, aortic dilation and aorto-left ventricular interaction - is getting more and more attention among cardiovascular physicians. This is the first book to refer for cardiologists, pediatric cardiologists, surgeons, ACHD specialists, etc. to acquire thorough knowledge on Aortopathy.

Advances in Endoscopy in Inflammatory Bowel Disease summarizes the recent progress made in endoscopy, an essential tool for the diagnosis and management of IBD. This book will significantly help all physicians, endoscopists and researchers working on GI endoscopy, especially those focusing on IBD, to improve their knowledge of IBD endoscopy.

This book, written by leading Japanese experts in the field, describes the latest findings on the neurotoxicity of anesthetics for the developing brain, postoperative delirium and cognitive dysfunction. It describes the risk factors for postoperative cognitive dysfunction in elderly surgical patients.

This book describes the latest modalities such as tau PET imaging for diagnosis of Alzheimer's disease and other dementias, and also provides information on handling and analyzing imaging data that is not found in other books.

This book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes. There are two parts in this book: Overview of the Human Genome (Part I) and The Human Genome Viewed through Genes (Part II). In Part I, after a brief review of human evolution and the human genome (by Naruya Saitou), chapters on rubbish or junk DNA (by Dan Graur), GC content heterogeneity (by Satoshi Oota), protein coding and RNA coding genes (by Tadashi Imanishi), duplicated genes (by Takashi Kitano), recombinations (by Montanucci and Bertranpetit), and copy number variations including microsatellites (by Naoko Takezaki) are discussed. Readers can obtain various new insights on the human genome from this part. In Part II, genes in X and Y chromosomes (by Yoko Satta and others), HLA genes (by Timothy A. Jinam), opsin genes (by Shoji Kawamura and Amanda D. Melin), genes related to phenotypic variations (by Ryosuke Kimura), transcription factors (by Mahoko Takahashi and So Nakagawa), diabetes-related genes (by Ituro Inoue), disease genes in general (by Ituro Inoue and Hirofumi Nakaoka), and microbial genomes (by Chaochun Wei) are discussed. The human genome sequences were determined in 2004, and after more than 10 years we are now beginning to understand the human genome from an evolutionary point of view. This book furnishes readers with a good summary of current research in the field.

Eight additional chapters are dedicated to the clinical and anatomical aspects of rectal cancer.In the last decade there has been an impressive evolution in the treatment of patients with rectal cancer, with a focus not only on the preservation of a cancer-free life, but the quality of that life.

This book presents a new view on the evolution of the brain, cognition, and emotion. Second, comparative neuroanatomists have accumulated a large amount of information about the brains of diverse animal groups to refute the old-fashioned idea that vertebrate brains evolved linearly from non-mammals to mammals.

This volume comprises eight papers delivered at the RIMS International Conference "Mathematical Challenges in a New Phase of Materials Science", Kyoto, August 4-8, 2014.

This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function.

Based on the increasing interdisciplinary nature of undergraduate and graduate programs, the primary goal of this present work is to serve as a comprehensive resource for senior-level undergraduates and for graduate students, particularly in polymer chemistry, materials science, bioconjugate chemistry, bioengineering, and biomaterials.

This book is dedicated to a specific component of paleoneurology, probably the most essential one: endocasts. Those who want to approach the field in general terms will find this book especially helpful, as will those researchers working with endocranial anatomy and brain evolution.

This book examines the importance of urban environmental management in the face of formidable challenges. It offers a comprehensive overview of science and policy, with discussion of relevant traditional and contemporary technologies.

In many Asian cities, groundwater is not only the source of domestic water but also an important resource for industrial development, making better management of groundwater resources essential for sustainable development.

This book considers the use of spatial data infrastructure in both the study and practice of urban regeneration. Topics range from the development of spatial data infrastructure to its application to urban regeneration studies.

This volume is a collection of Nishina Memorial Lectures delivered by distinguished physicists during the past 50 years at the invitation of the Nishina Memorial Foundation. You can read the remainder of this lecture and all other lectures online via the link under "E-content".

In developing countries, vulnerable urban space can be observed typically as substandard informal settlements such as slums or areas occupied by squatters. This book combines empirical and comparative analysis of improvement of vulnerable urban space and post-disaster rehabilitation in Asian and Latin American countries.

Flux dynamics is a well-known new problem in which flux creep and irreversibility line features are especially important for a fundamental understanding of the critical current and flux pinning.

This book covers all research fields in high Tc Superconductivity. Breakthrougs in the single crystal growth of a monolithic device leads to a new technology.

It is often said that these days there are too many conferences on general areas of computational mechanics. the first international scientific conference ever held was the Karlsruhe Congress of Chemists. Pais goes on to note: "The conference did not at once succeed in bringing chemists closer together ...

The pathology of congenital heart disease has attracted much attention over the past years, as exemplified by various excellent textbooks. Most texts include a description of the position and course of the atrioventricular con­ duction tissues, but usually propose rules in a general setting. No systematic and meticulous description of the atrioventricular conduction tissues as they relate to the margins of septal defects in various types of congenital cardiac malformations is, to the best of our knowledge, yet available. Such detailed information is of value for cardiologists, pathologists, and surgeons alike. The cardiologist needs the information for electrophysio­ logical studies, including electrocardiographic tracings, as one of the tools in refining diagnosis. The pathologist should have a full understanding of the disposition of the atrioventricular conduction tissues in complex congenital malformations, not only in order to able to communicate with cardiologists and cardiac surgeons in a given case, but also because pathologists are in a unique position to enhance the understanding of atrioventricular conduction in complex congenital heart disease by means of continuous close cooperation with those in the clinical and surgical arena. For the surgeon, in-depth knowledge of atrioventricular conduction and its variability is imperative, particularly in view of the ongoing refinements in surgical techniques and options for repair, as well as improvements in the understanding of preopera­ tive and postoperative cardiac performance.

Rapid advances in the study of the molecular basis of mammalian cell proliferation, differentiation, and apoptosis have made it possible to develop new screening systems for isolating from microbial metabolites specific inhibitors of mammalian cell functions.

This book explores new points of view of human memory in the link among mind, brain, and society. Research of human memory traditionally has been in the field of experimental psychology, and a number of psychological researchers have come upon important findings regarding human memory.

This book presents the latest research advances in the theory, design, control, and application of robot systems intended for a variety of purposes such as manipulation, manufacturing, automation, surgery, locomotion, and biomechanics.

This book focuses on actual morphofunctional findings of cells and tissues in living animal organs. The book also makes the management of living animal morphology more accessible not only for biomedical researchers but also for clinical doctors, providing a valuable resource work on the current perspectives of in vivo morphology.