Fysiologi

This third edition of the book offers an up-to-date review of Diabetes Mellitus with a focus on both Micro- and Macrovascular Disease. The text includes a review of the basic concepts of : Diabetes and Vascular Disease, including Endothelial Dysfunction; The Effect of Insulin on the Vascular System; The Mechanism of Atherosclerosis in Diabetes Mellitus and the Role of Inflammation on the Vascular Tree; and The Role of the Renin-Angiotensin-Aldosteronism on Diabetes Mellitus. Chapters will discuss the Genetics of Type 2 Diabetes Mellitus as well as the Metabolic Syndrome. Other chapters discuss the Risk Factors of Diabetes and Vascular Disease, including Hypertension; Dyslipidemia; and Thrombosis. The book also reviews Microcirculation; Diabetic Nephropathy; Diabetic Retinopathy; as well as the Epidemiology, Diagnosis, and Treatment of Peripheral Vascular Disease; Diabetes and Coronary Artery Disease; Diabetes and Percutaneous Interventions; Diabetes and Cardiac Surgery; and Diabetes and Heart Failure. Chapters conclude with a review of the present-day Treatment of the Diabetic Patient. Diabetes and Cardiovascular Disease, 3rd Edition, offers practicing physicians a cutting-edge scientific and clinical review of diabetic cardiovascular disease, providing both a deeper understanding of its pathology and all the day-to-day practical knowledge needed to treat patients effectively.

This contributed volume presents the current state of research on regenerative rehabilitation across a broad range of neuro- and musculoskeletal tissues. At its core, the primary goal of regenerative rehabilitation is to restore function after damage to bones, skeletal muscles, cartilage, ligaments/tendons, or tissues of the central and peripheral nervous systems. The authors describe the physiology of these neuro- and musculoskeletal tissue types and their inherent plasticity. The latter quality is what enables these tissues to adapt to mechanical and/or chemical cues to improve functional capacity. As a result, readers will learn how regenerative rehabilitation exploits that quality, to trigger positive changes in tissue function. Combining basic, translational, and clinical aspects of the topic, the book offers a valuable resource for both scientists and clinicians in the regenerative rehabilitation field.

In this issue, guest editors bring their considerable expertise to this important topic. Contains 12 practice-oriented topics including thyroid and aging; obesity and aging; hypothalamus-pituitary-adrenal axis and aging; male reproduction and aging; osteoporosis and aging; prediabetes and aging; and more.  Provides in-depth clinical reviews on endocrinology of the aging patient, offering actionable insights for clinical practice.  Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Dieses Buch versteht sich als ein umfassender Leitfaden für Sport- und Gesundheitsexpert*innen, Studierende, Wissenschaftler*innen, Trainer*innen, Athlet*innen verschiedener Sportarten und für alle, die ein allgemeines Interesse an gleichzeitigem Ausdauer- und Krafttraining haben. Nach einem kurzen historischen Überblick über die wissenschaftlichen Fortschritte zum kombinierten Ausdauer- und Krafttraining über die letzten Jahrzehnte werden in Abschnitt 1 die epigenetischen sowie physiologischen und neuromuskulären Unterschiede von Ausdauer- und Krafttraining erörtert. Anschließend wird in Abschnitt 2 eine aktuelle Analyse der bestehenden Erklärungsansätze für das Interferenzphänomen vorgenommen, während in Abschnitt 3 die trainingsmethodischen Besonderheiten des kombinierten Ausdauer- und Krafttrainings erläutert werden. In den Abschnitten 4 und 5 werden die theoretischen Überlegungen aus den vorangegangenen Abschnitten im Anschluss praktisch auf verschiedenste Zielgruppen angewandt, von Kindern und älteren Menschen bis hin zu Sportlern verschiedener Sportarten.Kombiniertes Ausdauer- und Krafttraining: Wissenschaftliche Grundlagen und Ableitungen für die Trainingspraxis ist ein neuartiges Buch zu einem der umstrittensten Themen der Sport- und Trainingswissenschaft. Oberstes Ziel der Herausgeber ist es, dieses Buch zu einem leicht verständlichen und gleichzeitig wissenschaftlich fundierten Leitfaden für die tägliche Praxis zu machen.

This third and final volume in the "e;Ion Transport in Tumor Biology"e; collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na+, K+, Ca2+, and Cl- channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic effects resulting from the combined use of classical cytostatics with ion transport-inhibiting drugs are pointed out, and the capability of bispecific antibodies to function as anticancer drugs is discussed. As readers will also learn, the use of ion channel inhibitors could improve the outcome of radiotherapy because the development of radio-resistance during radiotherapeutic treatment often correlates with increases in the expression levels and conductance of ion channels. The translational topics of this volume form a bridge between biochemical research and therapeutic application.As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.

Many significant achievements in new ultrasound technologies to measure bone and models to elucidate the interaction and the propagation of ultrasonic waves in complex bone structures have been reported over the past ten years. Impaired bone remodeling affects not only the trabecular compartment but also the cortical one. Despite the crucial contribution of the cortical structure to the whole bone mechanical competence, cortical bone was understudied for a long time. A paradigm shift occurred around 2010, with a special focus placed on the importance of cortical bone. This has sparkled a great deal of interest in new ultrasound techniques to assess cortical bone. While our book 'Bone Quantitative Ultrasound' published in 2011 emphasized techniques to measure trabecular bone, this new book is devoted for a large part to the technologies introduced recently to measure cortical bone. These include resonant ultrasound spectroscopy, guided waves, scattering, and pulse-echo and tomography imaging techniques. Instrumentation, signal processing techniques and models used are detailed. Importantly, the data accumulated in recent years  such as anisotropic stiffness, elastic engineering moduli, compression and shear wave speeds of cortical bones from various skeletal sites are presented comprehensively. A few chapters deal with the recent developments achieved in quantitative ultrasound of trabecular bone. These include (i) scattering-based approaches and their application to measure skeletal sites such as the spine and proximal femur and (ii) approaches exploiting the poro-elastic nature of bone. While bone fragility and osteoporosis are still the main motivation for developing bone QUS, this Book also includes chapters reporting ultrasound techniques developed for other applications of high interest such as 3-D imaging of the spine, assessment of implant stability and transcranial brain imaging.This book, together with the book 'Bone Quantitative Ultrasound' published in 2011 will provide a comprehensive overview of the methods and principles used in bone quantitative ultrasound and will be a benchmark for all novice or experienced researchers in the field.The book will offer recent experimental results and theoretical concepts developed so far and would be intended for researchers, graduate or undergraduate students, engineers, and clinicians who are involved in the field.The book should be considered as a complement to the first book publisher in 2011, rather than a second edition, in the sense that basic notions already presented in the first book are not repeated.

Discover the world of Giants and Dwarfs in this revised and first illustrated edition of the classic 1868 book by Edward J. Wood. This fascinating and rare collection of accounts brings to life both mythical and many historical figures, including the infamous Gogmagog and Polyphemus. Explore the chapter entitled "Bible Dwarfs" featuring the biblical hybrid giants known as the Nephilim, as well as forgotten legends and eyewitness accounts of famous dwarfs and giants.While the book may not fully reflect modern understanding of the medical and physical causes of dwarfism and gigantism, it offers a valuable archive of historical references, folklore, and accounts of the daily lives of these captivating figures. Many dwarfs and giants had dramatic life stories, solely due to their deviating size. They appeared in royal households, became attractions at traveling carnivals and exhibitions, or simply tried to create a normal life for themselves. From famous figures in lore to the more obscure, and even strange mummified bodies, this book offers a glimpse into an intriguing and often misunderstood world. Divided into 16 chapters, an appendix, and featuring 30 historical illustrations, this revised edition is both compelling and essential for anyone interested in exploring this unique chapter of human history.Revised & illustrated edition. Full table of contents on vamzzz.com

This book provides an overview of the metabolism of dietary compounds by the intestinal microbiota, and on the consequences of such metabolic activity on host metabolism and physiological functions; both in intestinal and peripheral tissues.Over the last years, our understanding of the causal links between microbiota metabolic activity towards dietary and endogenous substrates and human health status has evolved extensively. In this context, the book starts with a comprehensive introduction devoted to the physiological and metabolic functions of the intestinal epithelium, followed by a part dedicated to the way intestine offers board and lodging for microbes being on a short- or long-term stay. The next chapters focus on the utilization of the available substrates from diet by the intestinal bacteria to produce numerous bacterial metabolites, and on the impact of such microbial activity, in the first place for communication between microbes, and for communication between microbes and lodging host. As will be detailed, this latter process of interkingdom communication leads to either beneficial or deleterious effects on intestinal physiology and metabolism. Special attention is given to selected pathophysiological processes namely chronic intestinal inflammation, colorectal carcinogenesis, and diarrhea. Then, the effects of modifications of bacterial metabolites and other bioactive compounds by the host after intestinal absorption, and consequences for peripheral tissue functions are presented.Summarizing the state of the art on what is known about the metabolic crosstalk between gut microbiota and human metabolism, as well as perspectives for further experimental and clinical research, this book provides a useful resource for researchers, professionals, and students with a background in biology, and/or nutrition, medicine, pharmacology, and for those which are involved in the agriculture and food production. By explaining technical terms all along the text, this book should be understandable also for interested non-specialists.

Diabetic foot ulcers are a common complication of diabetes, and their treatment depends on the underlying causes. This book provides a basic understanding of diabetic foot ulcers (DFUs), including their pathophysiology, assessment, and treatment. Chapters present recent research findings with a focus on advancements in the treatment of DFUs, such as point-of-care devices for use at home and in the clinic.

Lifestyle-related diseases are caused by an unbalanced diet and irregular, undesirable lifestyle, leading to a condition called metabolic syndrome. Rather like dominoes falling, these diseases develop one after another. Owing to changes in dietary habits and working environments, the incidence of lifestyle-related diseases, obesity, and metabolic syndrome is increasing globally, resulting in a serious social problem that needs to be solved. This book deals with recent studies on lifestyle-related diseases and metabolic syndrome, and the following three topics are discussed: (1) characteristics of metabolic syndrome and lifestyle-related diseases; (2) the relationship between metabolic syndrome and several diseases; and (3) effective interventions to prevent lifestyle-related diseases. This book provides new ideas for the treatment and prevention of metabolic syndrome and lifestyle-related diseases.

Melatonin is a powerful hormone and antioxidant with numerous effects on metabolism and human health. Available as a dietary supplement for many years, it is one of the most popular over-the-counter alternative medicines available. Featuring contributions from researchers investigating the role of melatonin in various diseases and physiological conditions, this comprehensive book offers a wide range of expert reviews on the synthesis, regulation, and physiological effects of melatonin as well as its role in various diseases.

Estrogen - Recent Advances explores the role of estrogen in many disease processes and organ systems. Chapters discuss G-protein estrogen receptor signaling and estrogen's effect on the oral cavity, olfactory mucosae, and the prostate. The book presents cutting-edge research and developments in the field. Understanding the many effects estrogen has on the body will help the reader better understand disease processes and provide a framework for future discoveries.

Management of hypoglycemia in diabetes mellitus is a landmark achievement, especially in patients who take insulin. This book provides a comprehensive overview of hypoglycemia, including its pathophysiology, causes, clinical manifestations, management, and screening. It presents recent findings and research in the field and discusses new advancements in hypoglycemic control, including recently developed point-of-care devices for the home and the clinic.

Increasing human migrations, technological advances, agricultural activities, and climate change are forcing plants to adapt to new environments. This book highlights current morphological, anatomical, physiological, molecular, and genomic advances in plant defense mechanisms. These advances, including epigenetic mechanisms, have been linked to observed phenotypic plant plasticity. The book also outlines next-generation food systems, considering the resilience and sustainability of plant genomes and epigenomes.

The physiological or pathological variations in the amount or mass of each component of body weight can lead to an increase or a decrease in total body weight, with a potential risk of increased morbidity and mortality. This book presents an overview of current knowledge about different types of body weight changes, with a special emphasis on obesity.

This latest offering from the highly regarded Ross & Wilson stable provides a sound, evidence-based grounding in pathophysiology for anyone studying or working in the allied health professions It covers normal physiology and the associated pathophysiological processes that lead to disease. The underlying science is clearly explained and linked to clinical situations, relating the changes in normal physiological function directly to onset and progress of disease, providing the exact level of detail you'll need in your professional practice. Ross & Wilson's Pathophysiology is clearly written and easy to understand, with beautiful illustrations and enhanced navigation to make learning this important subject a pleasure. Clear, engaging and straightforward writing style - suitable for nurses as well as paramedics, physiotherapists, midwives, radiographers and clinical physiologists Comprehensive explanations of the underlying science, linked to clinical scenarios so readers can relate learning to practice Cross-referencing to allow for easy navigation across different sections Draws on the latest evidence and up-to-date research Beautifully illustrated with clear, well-labelled figures, photographs and diagrams

Approx. 538 pages Specifically designed to enable student paramedics to fully appreciate the human body and its functioning Guides the reader through different regions of the body in a logical and coherent way Covers anatomy first, followed by the physiology of the various structures Extensive cross referencing to other relevant regions to enable full understanding of these both individually and in connection to one another Clearly written text supported by relevant and informative illustrations Text boxes covering applied anatomy, clinical anatomy, applied physiology and clinical physiology Self-test multiple choice questions in each chapter

Wie beeinflussen Lebensmittelkomponenten und -inhaltsstoffe die Immunantwort? Welche Rolle spielt das Mikrobiom des Darms bei der Entstehung von Erkrankungen? Kann die Funktion des Immunsystems durch eine bestimmte Ernährungsweise positiv stimuliert werden? Dieses farbige, gut zu lesende Lehrbuch diskutiert auf einem aktuellen Niveau die Einflüsse von Lebensmittelinhaltsstoffen auf die biochemisch-, zellulär-regulatorischen und genetischen Abläufe der gesamten Immunabwehr. Schwierige Sachverhalte werden durch Leitfragen und Definitionsboxen verständlich vermittelt. Exemplarisch dargestellte Krankheitsbilder zeigen Anwendungsmöglichkeiten für funktionale Lebensmittel auf. Exkurse geben technologische, rechtliche und ethische Einblicke in die Entwicklung von Supplementen, Nutraceuticals und Healthfood.Pointierte Zusammenfassungen, Wirkstoffauflistungen und ein Fachbegriffglossar zeichnen dieses Lehrbuch auch als Referenz- und Nachschlagewerk aus.Besonders hervorzuheben sind zudem über 30 kurze Lehrvideos, in denen zelluläre und molekulare Interaktionen animiert erläutert werden. Dieses Lehrbuch spricht alle Studierenden und Berufstätigen an, die sich mit Ernährung und Gesundheit beschäftigen.

The goal of this book is not to "prove" there is a God. The goal is to amaze you with the fact that almost nothing in life is really "simple," and the most logical, rational explanation is that God created everything.

Looking for a comprehensive (127 pages) Coloring +Facts/Theory+ MCQ (Multiple Choice Question) book on Anatomy & Physiology with colored interiors,45 coloring pages, and 30 Multiple Choice Questions?All the subject matter experts agree on the fact that complex learning which involves the visual coloring effect as a differentiator leaves a lasting impression on the brain. Also, it makes the topic more interesting.This book is a perfect gift to Medical School Students, Nurses, Doctors, Teens, and Adults who are interested in learning about Human Anatomy and Physiology.The Theory & MCQ part is unique which makes the learning tested and revised for the long term.The last chapter consists of basic terminologies of anatomy.What makes this book comprehensive is:127 pages of comprehensive step-by-step Anatomy knowledgeBasic Anatomy & Physiology theory covered in each section45 coloring pages with a different topic30 + MCQ (Multiple Choice Questions) with SolutionSpace to make some notes on each topicDetailed drawing of all sections to make a lasting impression for long-term recallThis is a unique book with all interiors in color and colored photos provided for each coloring page.The sections of Anatomy & Physiology covered are:1. Introduction & History2. Levels of organization of the Body3. Body Cavities4. The Integumentary System5. The Skeletal System6. The Muscular System7. The Nervous System8. The Endocrine System9. The Circulatory System10. The Lymphatic System11. The Respiratory System12. The Digestive System13. The Urinary System14. The Reproductive System15. Basic TerminologiesSo, what are you waiting for? Learn Human Anatomy & Physiology with ease!

Kettlebell Strength Training Anatomy provides you with an inside look at kettlebell training. With 50 exercises and over 100 full-color anatomical illustrations, this in-depth guide will help you understand the link between training, strength, and performance.

This book reviews the science of multidirectional speed and translates this information into real-world application to provide a resource for practitioners to develop multidirectional speed with athletes.

This book sheds new light on the history of exercise physiology and how it essentially grew, thanks to the work of a few major Schools. Analysing and interpreting the evolution of the field, the authors focus on the School of Milano, which was founded by Rodolfo Margaria and is one of the most prominent representatives, having played a central role in promoting and advancing this field of physiology. In turn, the authors trace Margariäs biography; under his influence, the school introduced new concepts with regard to both the energetics of muscular exercise and to human locomotion. These concepts were further developed by Margariäs pupils and by subsequent generations. Indeed, the course that was set in Milano greatly influenced the entire history of modern physiology. Readers with a keen interest in the origins of modern concepts and technologies in exercise physiology will find this book a fascinating and informative read.

This book of the series on ¿Advances in Biochemistry in Health and Disease¿ includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters. This book has been organized into three sections: (i) General Implications of RAS in human health and Infectious Diseases, (ii) Lung, Liver and Kidney Diseases, and (iii) Development of Cancer. Each chapter has discussed comprehensive knowledge regarding the molecular and cellular aspects of the role of RAS in the pathophysiology and pharmacotherapy of different disease processes. Biochemical mechanisms associated with angiotensin II type 1 and type II receptors, and angiotensin (1-7) MAS receptors for the occurrence of both harmful and beneficial effects of prolonged activation of RAS in different diseases have been outlined. It is noteworthy to point out that different chapter in this book were prepared by recognized global expertise in the area of inflammation, oxidative stress and signal transduction pathways to highlight the role of RAS in different diseases. It is our sincere hope that this book will be of great interest to both biomedical investigators and health professionals as well as graduate students and postdoctoral fellows all over the world.

"An arresting illustrated history of twins in mythology, science, and visual culture. Twins have captivated the imagination for centuries, occupying a unique place in our cultural and scientific history. Twinkind looks at twins in myth and legend; anatomy, sociology, and genetics; and as sources of spectacle, entertainment, and community. A visual journey like no other, this book sheds critical light on the competing visions of twins around the world and throughout history, showing how the lived experience of twinkind has elicited profound attraction and respect, but also puzzlement, fear, and fascination."--