Fysiologi

This handbook supports the identification of inappropriate work design in manual materials handling and thus the prevention of overloading the body and of the development of health disorders. The approach at hand, The Dortmund Lumbar Load Atlas, is focussed exclusively on biomechanical aspects of loading, overload criteria and signs of overloading in the form of verifiable low-back diseases due its strikingly frequently affectedness.Manual materials handling is understood to be the holding, lifting or lowering, pulling or pushing as well as carrying of load objects and thus the application of forces mostly with one or both hands on the item handled. Due to the biomechanical similarity, special handling tasks are also addressed, such as shoveling bulk material, transporting goods via wheelbarrow and moving people manually in the care sector.The book aims to promote interest in biomechanical approaches and provides information to all persons involved in the design, evaluation and redesign of manual materials handling, e.g. ergonomists, occupational physicians, orthopaedists, employers or researchers, lecturers and students. This handbook enables analysis of manual materials handlings regarding potential lumbar overload and contains the following:a comprehensive collection of data on lumbar load in typical manual materials handling activities¿a load register on interbranch activities,synopses of previously analysed biomechanically challenging occupational activities¿a load register on branch-specific activities,explanations of the methodological approach to predicting moments and forces as well as their components in relation to the lumbar spine via biomechanical modelling andcriteria for the evaluation of load data with regard to potential lumbar overloading during single operations, working shifts and the entire occupational life.Thenew recommendations on maximum daily exposure for lifelong work for both men and women are bridging the former gap of biomechanically justified action frequency limits and now offer the possibility of a completely biomechanical path for risk assessment of manual materials handling. The book provides hence a serious contribution to the objectification of lumbar load and load-bearing capacity aiming at an ergonomic work design of manual materials handling for short- as well as long-term exposures.

This book entitled "Nitric Oxide: From Research to Therapeutics" includes the most recent information about the role of Nitric Oxide (NO) in physiology, pathophysiology and its translation to therapeutics. The Editors are vastly experienced in the field of NO research. The international panels of contributors to the various chapters of the book are all well-established researchers and health professionals who have worked in different areas of NO physiology and pathophysiology, and have made a considerable impact in the field. The book is a comprehensive collection of the most recent information on NO as a physiological regulator and its diverse potential as a therapeutic target for the treatment for a variety of disease states. This compilation is aimed at professionals and students from both academia and the industry in the areas of basic biomedical and clinical sciences.

"Explore new movements and alleviate stiff joints with more than 100 exercises designed to keep you flexible, energized, and active for life"--Provided by publisher.

This volume presents selected papers presented during the 16th International Conference on Humanizing Work and Work Environment (HWWE 2018). The book presents a confluence of ideas on ergonomics and technology implementation to improve workplace environments and work systems to maximize effectiveness and performance. The volume is thematically arranged, with papers covering different aspects of ergonomics and design. The volume will be of use to researchers, practitioners and students working in different fields of ergonomics.

This detailed volume explores techniques for researching brown adipose tissue (BAT) and the fascinating biology and therapeutic potential of thermogenic adipocytes. The content reflects the advancing technologies in genetics, imaging, and 'omics strategies that are allowing researchers to probe BAT biology at unprecedented depths and detail, yet it also presents classic physiology principles, which remain the core tenets of BAT biology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Brown Adipose Tissue: Methods and Protocols provides perspectives and detailed protocols for the benefit of both new BAT researchers looking for guidance as well as seasoned researchers who would like to expand their toolkits. Chapter 12 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Exercise Physiology: For Health and Sports Performance brings together the essential human anatomy and applied physiology that students of exercise science, physical education and sports coaching will need to know.

Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers, and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics. Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure.

Migraine Management, Volume 199 covers the effective treatment of migraines, including different subtypes of migraines in different patient populations. The classification and diagnostic criteria of common and uncommon subtypes of migraine is explored in detail, including childhood variants. An in-depth analysis of the pharmacology of acute and prophylactic agents is presented, along with an evidence-based review of pharmacologic management. This includes recently developed CGRP monoclonal antibodies and non-peptide small molecule CGRP antagonists. Advances in neuromodulatory treatments, both noninvasive and implantable are also critically reviewed. Finally, specific treatment-related issues in pregnancy and lactation and childhood as well as the elderly are covered. Issues related to the diagnosis and management of vestibular migraine and the co-morbid disorder of persistent postural-perceptual dizziness are also explored.

Migraine Biology, Diagnosis, and Co-Morbidities, Volume 198 covers a wide range of issues related to migraine. The epidemiology, global, and personal impacts of migraine are covered, including topics on the pathophysiology of migraine and migraine aura, the pathophysiology of the associated symptoms of photophobia and phonophobia, and the genetics of migraine. The classification and diagnostic criteria of common and uncommon subtypes of migraine are also explored in detail, including childhood variants. Issues related to the diagnosis and management of vestibular migraine and the co-morbid disorder of persistent postural-perceptual dizziness are also covered. Finally, the important comorbidities of migraine such as anxiety, depression and other forms of chronic pain are discussed, along with the current state and future directions of migraine research and management.

Cliffsnotes quick review books give you a clear, concise, easy to use review of the basics. Introducing each topic, defining key terms, and carefully walking you through each sample problem, these guides help you grasp and understand the important concepts needed to succeed.