Endokrinologi

The pituitary gland is often referred to as the master gland, coordinating hormonal signals from the hypothalamus and peripheral circulation to maintain homeostasis in the body. Patients with pituitary dysfunction are faced with challenges unique to each stage of their life cycle. For example, the goals of management for a hypopituitary adolescent transitioning to adulthood would be to optimize growth and sexual development. In early adulthood, approaches that optimize of fertility in men and women can be a priority, and the management approach will be very different from that of older adults requiring sex hormone replacement. This case-based guide will provide practical clinical guidance on approaches to the management of pituitary disorders organized by time of life, from childhood and fertile years through to older age. Sensibly divided into sections, various pituitary disorders and conditions are described and relevant treatment strategies are outlined. Sections included discussions of the unique considerations for the pituitary gland in childhood and adolescents, patients desiring fertility and pregnant patients, health optimization and non-tumoral diagnoses in adults, and management of disorders of the hypothalamic-pituitary axis in the elderly. Each chapter presents a clinical case vignette as an introduction to the concepts and a framework for the discussion of the diagnosis, management and unique consideration of each pituitary pathology. Practical and user-friendly, Pituitary Disorders throughout the Life Cycle is an excellent resource for practicing clinical endocrinologists (pediatric, transitional care, adult) and reproductive endocrinologists as well as specialty residents and trainees.

The book offers a comprehensive overview of all parathyroid gland disorders both, benign and malignant.  It emphases established concepts, presents the ongoing controversies, challenges and debates on diagnosis and treatment of different parathyroid gland disorders, with a view of clarifying some uncertainties, making suggestions to resolve others, and establishing strategies to reach therapeutic success.In addition to general information on parathyroid gland embryology, surgical anatomy, histology and physiology, the chapters explore hyperparathyroidism, osteitis fibrosa cystica, hypoparathyroidism, hungry bone syndrome, the importance of calcium in the human body and differential diagnosis of hypercalcemia. The last chapters investigate post-thyroidectomy hypocalcemia, thyroid cancer, recent intra-operative localizing tools, and illustrate new techniques of parathyroidectomy, as well as parathyroid transplantation. The book will be an invaluable and indispensable source of knowledge and reference for all specialists and trainees entrusted with the care of patients suffering from parathyroid disease.

This book evaluates muscle and nerve biopsies. It creates a more analytical view of neuromuscular diseases in the light of clinical findings. Diseases that occur mostly in muscle or nerve tissue may show common clinical findings. Addressing these two issues together will make it easier to understand the diseases. Neuromuscular diseases, normal histology, embryology, and physiopathology of muscles and nerves are discussed with a main focus on differential diagnosis. The book also presents the most cost-effective and easiest-to-follow algorithms for the differential diagnosis of diseases.

This book considers the family doctor relationship and the process of ending that relationship. What happens when a family doctor or someone like them, deeply committed to long-term relationships, decides to end those commitments? What¿s involved? What are the embodied experiences for doctor and patient, for doctor and staff, for physician leader and others? What comes next? This book invites the reader to immerse in personal stories and reflections of family physicians who choose to retire from practice, depart long-standing leadership roles, or shift from one place of deep relational commitments to something else. These stories concern the particulars of family medicine and general practice, but they share much with any vocation rooted in the duties, challenges, and rewards of relationships bound by covenant and not transaction. This book is relevant to all professionals involved in healing relationships.

Dr. Beatriz Olson unravels the "secrets" of our ancestral biology and survival mentality.