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This book will provide readers with a good overview of some of the most recent advances in the field of detector technology for gamma-ray imaging, especially as it pertains to new applications. There will be a good mixture of general chapters in both technology and applications in medical imaging and industrial testing. The book will have an in-depth review of the research topics from world-leading specialists in the field. The conversion of the gamma-ray signal into analog/digital value will be covered in some chapters. Some would also provide a review of CMOS chips for gamma-ray image sensors.
This superbly illustrated book examines all aspects of the use of modern post-mortem imaging in forensic investigations, which has flourished since the introduction of multidetector computed tomography and magnetic resonance imaging. Readers will find guidance on the applications of all relevant imaging modalities and contrast media. Analogies and differences between forensic and clinical imaging are highlighted, and it is explained what lessons forensic imaging holds for clinical radiology, and vice versa. The remainder of the book comprehensively documents the typical "e;normal"e; post-mortem findings and the imaging presentations in various forms of trauma and nontraumatic forensic cases, including those in which medical liability may be an issue. The authors are radiologists and forensic radiologists from across the world who have extensive experience in post-mortem imaging. The book is primarily intended for forensic pathologists, radiologists, and radiographers seeking practical information on forensic imaging, but it will also be of interest to others, such as lawyers, who encounter this specialty during their professional activities.
This book offers a practical guidance to healthcare professionals interested in learning how to make adequate clinically-oriented use of cardiovascular MRI. Thanks to its case-based approach, it provides a detailed guide to MRI applications in the most common clinical cardiovascular scenarios. Chapters describe a number of real clinical cases, including concise clinical data, clear descriptions of the most relevant information obtained from MRI and of their meaning in terms of patient management. Emphasis is placed on traditional as well as newer MRI techniques, always keeping a practical format, focused on the hands-on knowledge required for an accurate image interpretation. In the online version, the text of each case is supplemented with additional images and videos, certainly making this book a useful resource for understanding how MRI principles apply to real clinical cardiovascular situations.
This open access book provides basic concepts on Integrated Diagnostics and Theranostics with special emphasis on different human thyroid diseases. Thyroid diseases are increasingly detected (incidentally in many cases) but are clinically negligible in a significant proportion of patients. Accordingly, it is urgent to move from the simple disease detection to a reliable disease characterization in order to concentrate efforts on patients in need of tailored disease management. The current scenario of in vitro and in vivo diagnostics, is fastly moving toward the Integrated Diagnostics (i.e. convergence of imaging, pathology and laboratory tests with advanced information technology). Furthermore, the integration of different information will aid clinicians to properly select treatments and stratify patients¿ prognosis over time. Theranostics is a perfect paradigm of such integrated approach and radioiodine, indicated for benign and malignant thyroid disease management, was the first and is still the mostly used theranostic agent in medicine.Featuring basics concepts and clinical cases discussions the Atlas will be an invaluable tool for clinicians, laboratory specialists, imaging physicians and biomedical technologists involved in diagnosis and therapy of thyroid diseases.
This book, now in a revised third edition, provides practical guidance on the use of radiotherapy techniques in the management of benign diseases.In this edition, the content is grouped in chapters according to the disease category, including autoimmune disorders, dermatologic conditions, infectious diseases, inflammatory diseases, endocrinological disorders, musculoskeletal disorders, neurological disorders, benign lymphoid disorders, pain disorders, psychiatric disorders, reproductive topics, benign tumors/pre-malignant conditions, and vascular disorders. The format of the different sub-chapters follows those of the previous editions: Each of the sub-chapters features a brief summary, followed by explanatory tables and reference lists. This concise yet comprehensive book is an invaluable resource for radiation oncologists.
This detailed volume explores key concepts and experimental design related to Positron Emission Tomography (PET) imaging that have revolutionized our understanding of human biology. The first part focuses on recent advances in radiotracer probe development to enable the detection of materials, from large macromolecules to complicated drug-like structures. The next section describes how key physiological and pathophysiological processes can be interrogated and quantifiably measured with this imaging technique. Finally, chapters examine important technological developments in the field that are revolutionizing the way these innovative PET probes are utilized in the clinic. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Positron Emission Tomography: Methods and Protocols serves as an ideal guide for researchers looking to use imaging to revolutionize the way we diagnose and treat disease.
In this issue of Radiologic Clinics, guest editors Drs. Nicola Schieda and Andrei Purysko bring their considerable expertise to the topic of Prostate Imaging. Worldwide, prostate cancer is the second most common cancer diagnosed in males, and MRI scans can give doctors a very clear picture of the prostate and nearby areas. In this issue, top experts discuss key topics such as a contemporary approach to prostate imaging and data reporting system score 3 lesions; the expanding role of MRI and use of PRECISE criteria in the active surveillance of prostate cancer; MRI-guided prostate cancer therapies; and more.Contains 12 relevant, practice-oriented topics, including update on optimization of prostate MRI technique and image quality; prostate imaging and data reporting system (PI-RADS) Version 2.1 pitfalls in prostate MRI interpretation; prostate cancer staging with MRI; PSMA PET: pearls and pitfalls; and more.Provides in-depth clinical reviews on prostate imaging, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
The book provides, in a comprehensive yet concise way, essential information to improve the knowledge and skills of all healthcare providers involved in the treatment of patients with breast cancer. The content does not focus on general information that is widely available via different sources, but on technical aspects - "e;hands-on"e; daily practices and principles of radiation oncology that are not included in other books. Drawing on information taught in courses at e.g. the ESTRO School, as well as the authors' broad clinical experience, the respective contributions reflect and share the expertise of leading experts in breast cancer radiation therapy, supported by sound data and evidence. Each chapter includes a short introduction summarizing the evidence in the literature and "e;pearls"e; (a short bullet-point summary), and is enriched by tables, figures and illustrations to provide a concise, easy-to-follow and appealing overview.The book, containing also useful electronic supplementary material, will be of interest to a wide range of readers, including radiation oncologists, radiation technicians, medical physicists, and others involved in breast cancer care.
Distilling all of the most important content from Dr. Donald L. Resnick's highly esteemed, five-volume Diagnosis of Bone and Joint Disorders into a single, concise source, Bone and Joint Imaging, 4th Edition focuses on the specific, state-of-the-art musculoskeletal imaging and interpretation knowledge practitioners need today. This highly anticipated new edition has been fully revised from cover to cover for a remarkably thorough, yet focused and pragmatic, source of clinical guidance. Dr. Resnick’s carefully chosen editorial team, Drs. Jon A. Jacobson, Christine B. Chung, Mini N. Pathria (all former Resnick fellows) and Mark J. Kransdorf (co-author of the previous edition), are well-equipped to expertly address the many recent changes in musculoskeletal radiology since the previous edition. Authoritative, easy-to-read text and more than 3,800 exquisite images demonstrate every principle and capture the characteristic presentation of the wide range of disorders you’re most likely to encounter in everyday practice. Features a newly revised, streamlined organization with easy-to-digest sections on infection; trauma; osteoarticular, nerve, and muscle derangements; arthropathy; systemic diseases (metabolic, endocrine, hematologic, and connective tissue); tumors; interventional radiology; post-operative radiology; and pediatric imaging. Provides more than 2,100 outstanding images (1,300 are new) that depict important concepts, techniques, and findings in musculoskeletal imaging. Discusses the full range of diagnostic modalities, including advanced imaging methods and techniques and expanded content on MRI and ultrasound. Covers key introductory material on basic science, diagnostic techniques, imaging, and interventional procedures. A highly efficient review source for residency and radiology board examinations, as well as an indispensable reference for clinical practice. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Any additional digital ancillary content may publish up to 6 weeks following the publication date.
This book, now in an extensively revised second edition, is designed to provide the reader with a full understanding of the role of cone beam computed tomography (CBCT) in helping to solve many of the most challenging problems in endodontics. It will shorten the learning curve in application of this exciting imaging technology in a variety of contexts: difficult diagnostic cases, treatment planning, evaluation of internal tooth anatomy prior to root canal therapy, nonsurgical and surgical treatments, early detection and treatment of resorptive defects, and outcomes assessment. The ability to obtain an accurate 3D representation of a tooth and the surrounding structures by means of noninvasive CBCT imaging is changing the approach to clinical decision making in endodontics. Clinicians long accustomed to working in very small, three-dimensional spaces are no longer constrained by the limitations of two-dimensional imaging. The challenges of mastering the new technology can, however, be daunting. The detailed guidance contained in this book will help endodontists to take full advantage of the important benefits offered by CBCT.
The aim of this book is to provide crisp information related to pathology, management and radiological/molecular imaging in breast carcinoma, along with detailed information on FDG PET-CT in breast cancer, normal variants, artefacts, pitfalls with atlas illustrations. The book is unique in providing quick reference to practice of PET/CT in breast cancer. The initial few chapters are related to the pathology and management of breast carcinoma to help understand the pathophysiology of breast cancer before going to the imaging. The chapter on imaging in breast cancer highlights the role of different imaging modalities for different indications to the reader. The last four chapters describe in detail the role, normal variants, artefacts and pitfalls of FDG PET/CT along with recent molecular imaging advances in breast cancer.Written by Pathology, Oncology, Radiology and Nuclear Medicine experts from different countries with enormous experience in breast cancer practice, the book addresses nuclear medicine physicians and radiologists, but it may be of interest to a wider medical community, including oncologists and radiotherapists.
The early detection of lung cancer plays a crucial role in improving patient outcomes and increasing the chances of successful treatment. The innovative approach of "Neuro-Fuzzy Inference for Early Detection of Lung Cancer" presents a groundbreaking solution to identify potential lung cancer cases at their nascent stages.This novel method combines the power of neural networks and fuzzy logic to analyze complex medical data derived from lung imaging and patient history. By integrating these two intelligent techniques, the system can effectively extract meaningful patterns and insights from the data, enabling accurate and reliable lung cancer detection.The neuro-fuzzy inference approach enhances the system's ability to adapt and learn from new information, making it capable of detecting subtle abnormalities in lung images that might be indicative of early-stage cancer. This adaptive learning ensures a higher level of accuracy and a lower rate of false negatives, providing more opportunities for early intervention and timely medical attention.The early detection of lung cancer using this approach holds the potential to revolutionize oncology practices, as it empowers healthcare professionals to diagnose and initiate treatments during the initial stages of the disease. This can significantly improve patient prognosis and survival rates.Additionally, the neuro-fuzzy inference system can be integrated seamlessly into existing medical workflows, making it a valuable tool for radiologists and clinicians. Its user-friendly and efficient implementation expedites the diagnostic process and enhances the overall healthcare experience for both medical practitioners and patients.In summary, "Neuro-Fuzzy Inference for Early Lung Cancer Detection" presents a promising advancement in the fight against lung cancer. By leveraging the synergies of neural networks and fuzzy logic, this approach offers a powerful and sensitive tool to aid in the early detection and subsequent management of lung cancer, potentially saving countless lives.
This research focuses on enhancing the impact of 3D medical images through the application of segmentation techniques. 3D medical imaging plays a critical role in diagnosis, treatment planning, and surgical interventions. However, the complexity and size of 3D medical images can pose challenges in accurate interpretation and analysis.The study aims to enhance the impact and utility of 3D medical images by implementing advanced segmentation techniques. These techniques involve the extraction and delineation of specific structures or regions of interest within the images, such as organs, tumors, or blood vessels. The research will explore various segmentation methods, including region-based, boundary-based, and deep learning-based approaches.By effectively segmenting 3D medical images, the proposed techniques can improve visualization, facilitate quantitative analysis, and support more precise surgical interventions. The study will evaluate the performance and effectiveness of the enhanced segmentation techniques using metrics such as Dice coefficient, Jaccard index, and accuracy.The outcomes of this research have the potential to significantly impact the field of medical imaging. The improved segmentation techniques can aid radiologists, surgeons, and researchers in extracting valuable information from 3D medical images, leading to better diagnoses, treatment planning, and patient outcomes. Additionally, the findings may contribute to the development of automated systems that can assist in real-time segmentation and analysis of 3D medical images, enhancing efficiency and accuracy.In summary, this research aims to enhance the impact and utility of 3D medical images through the implementation of advanced segmentation techniques. The outcomes can have a positive impact on healthcare by improving the interpretation, analysis, and utilization of 3D medical imaging, ultimately leading to improved patient care and outcomes.
Disorders of the spinal cord are diverse and potentially devastating. They can present as acute, subacute and chronic disorders causing a variety of symptoms. Patients can present to pediatricians, internists, OBGYNs, emergency room physicians and neurologists requiring a diversity of clinicians to be familiar with the signs, symptoms, recommended testing and treatment options. This book comprehensively addresses myelopathies, the broad spectrum of potential pathologies. Chapters cover approaches to acute, subacute and chronic myelopathies; individual myelopathic disorders; the pathobiology, epidemiology, signs, and symptoms of the disorder; diagnostic approach, and therapeutic options. This comprehensive review is beneficial to any clinician, with special emphasis for neurologists, neurosurgeons, neuroradiologists and physiatrists.
This vastly illustrated book offers a comprehensive survey of the role of imaging in the diagnosis of synovial tumors and tumor-like conditions. It gives an overview of the anatomy and histology of the synovium and discusses the classification, pathology, genetics and molecular biology of synovial tumors. The book presents the benefits of various imaging modalities in the diagnosis of these masses, which is important to provide appropriate treatment.Imaging of Synovial Tumors and Tumor-like Conditions will be a valuable resource not only for radiologists but also for orthopedic surgeons, oncologists, radiotherapists, and pathologists.
This book offers a new edition of the hugely successful title, Imaging & Technology in Urology--Principles and Clinical Applications edited by Steve Payne, Ian Eardley, Kieran O'Flynn in 2012. Essential reading for preparation of exit exams in Urology, it is used worldwide by exam candidates. Fully updated in essential areas of the book following on from recent developments in the last decade, it helps give preparation to candidates. The most comprehensive and reliable source of information on this particular topic.
Medical Imaging Informatics is an edited book that discusses how medical images can be processed using machine learning techniques and big data analysis methods. These tools help physicians to gain a full overview of a patient's data, which in turn assists with diagnosis, prognosis or intervention.
This edited book explores new and emerging technologies in the field of medical image processing using deep learning models, neural networks and machine learning architectures. Multimodal medical imaging and optimisation techniques are discussed in relation to the advances, challenges and benefits of computer-aided diagnoses.
This book provides an extensive overview of the role of imaging in the detection, diagnosis, management, and follow-up of tuberculosis. Chapters cover the disease's epidemiology and pathophysiology, microbiological diagnosis and pathology relevant to radiologists, and the distinct aspects of imaging tuberculosis at various locations and body systems. This book discusses recent advances in imaging pertaining to tuberculosis, and addresses the approach to patients with tuberculosis and HIV co-infection. The final chapter offers an algorithmic approach to the diagnosis and management steps of tuberculosis. Imaging of Tuberculosis is an updated and comprehensive reference source that covers imaging of tuberculosis in a structured fashion and is valuable for radiologists.
This atlas is a detailed and complete guide on imaging of the dentomaxillofacial region, a region of high interest to a wide range of specialists. A large number of injuries and patient's treatment involve the facial skeleton. Enriched by radiographic images and illustrations, this book explores the anatomy of this region presenting its imaging characteristics through the most commonly available techniques (MDCT, CBCT, MRI and US). In addition, two special chapters on angiography and micro-CT expand the limits of dentomaxillofacial imaging. This comprehensive book will be an invaluable tool for radiologists, dentists, surgeons and ENT specialists in their training and daily practice.
This book covers every aspect of radiation myelopathy and considers the evidence from all species in which it has been studied. The historical and current understanding of the pathogenesis of this rare but devastating injury is first discussed. The evidence regarding the role of a variety of factors in radiation myelopathy is then reviewed. Readers will find detailed information on the impacts of total radiation dose, radiation volume, dose fractionation, hyper fractionation, age, anatomic level, comorbidities, radiation modifiers, other therapies, and retreatment of the spinal cord. Given the similarity of the pathogenesis of radiation myelopathy in humans and experimental animals, the potential for cross-species modelling of dose response is explored, with attention to relevant species differences. Treatment of the condition is also fully considered. New theories are presented regarding retreatment, small volume response, and the final step in white matter necrosis. The final chapter addresses the medicolegal issues elicited by radiation myelopathy, which is often the result of treatment error. Radiation Myelopathy will be of high value for radiation oncologists, radiation physicists, dosimetrists, biologists, neurologists, medical oncologists, and attorneys.
This book is an entirely revised second edition of "Imaging of the Knee", published in 2003, and provides an up-to-date comprehensive review of imaging and pathologies of the knee. In the first part of the book, the various techniques employed when imaging the knee are discussed in detail. Individual chapters are devoted to radiography, arthrography, computed tomography and CT arthrography, magnetic resonance imaging and MR arthrography, and ultrasonography. The second part then documents the application of these techniques to the diverse clinical problems and diseases encountered in the knee. Among the many topics addressed are congenital and developmental abnormalities, trauma, meniscal pathology, the cruciate and collateral ligaments, the postoperative knee, infection, arthritis, osteochondritis, osteonecrosis and tumors. Each chapter is written by an acknowledged expert in the field, and a wealth of illustrative material is included. This book will be of great value to radiologists and orthopaedic surgeons.
This book provides a comprehensive analysis of the value of contrast-enhanced ultrasound (CEUS) in the diagnosis of a wide variety of pathologies. Sonography reliably identifies a wide range of diseases, and the efficacy of modern ultrasound has dramatically improved with contrast enhancement.This book covers almost all aspects of CEUS starting from basic principles and ending with features of its application in individual organs. In particular, it explores the diseases of abdominal, retroperitoneal, and pelvic organs as well as superficial structures, highlighting the characteristic features of typical findings. Focal lesions are discussed in depth, with attention to their early detection and differential diagnosis. Besides, a practical approach to the stratification of the risk of malignancies is provided. The authors summarized their own experience with CEUS in oncology, hepatology, gynecology, urology, endocrinology, and other fields of medicine. The role of CEUS in differential diagnosis of various disorders of the female reproductive system is comprehensively discussed as well. The presentation is clear and concise, and richly illustrated.The book will be a helpful tool for both residents and practitioners approaching ultrasound diagnostics, as well for more experienced radiologists and other professionals.
This book presents multiple aspects of spine care from the perspective of different disciplines. It's organized by sections focused on non-operative care, spine injections and procedures, perioperative care, operative care, pediatric care, and special topics. Each chapter has been written by a clinician whose active practice involves the topic of their chapter. Practical and clinically relevant, this book educates any practitioner who cares for patients with back and neck pain and other spine conditions about implementing a multidisciplinary team to treat the spine.
Biomedical signals provide unprecedented insight into abnormal or anomalous neurological conditions. The computer-aided diagnosis (CAD) system plays a key role in detecting neurological abnormalities and improving diagnosis and treatment consistency in medicine. This book covers different aspects of biomedical signals-based systems used in the automatic detection/identification of neurological disorders. Several biomedical signals are introduced and analyzed, including electroencephalogram (EEG), electrocardiogram (ECG), heart rate (HR), magnetoencephalogram (MEG), and electromyogram (EMG). It explains the role of the CAD system in processing biomedical signals and the application to neurological disorder diagnosis. The book provides the basics of biomedical signal processing, optimization methods, and machine learning/deep learning techniques used in designing CAD systems for neurological disorders.
In this book recognized world-renowned expert authors expose the state of the art on musculoskeletal ultrasound elastography.Low cost, wide dissemination and accuracy in the evaluation of the musculoskeletal structures, nerves, periosseous soft parts, vascular structures, together with the possibility of performing real time dynamic studies, made the ultrasound technique widely spread among sonographers and musculoskeletal radiologists.Each chapter presents a description of the elastographic semiotics of the main pathologies of the musculoskeletal system and soft tissue, images that represent both routine and more complex clinical cases in a practical and schematic way and summary tables on the characteristics in terms of elasticity found in the main pathologies.A wealth of color images as well as dynamic images and tables complete the book, that will be a useful tool for sonographers , radiologists, orthopedists, sports medicine specialists wishing to expand their knowledge on ultrasound elastography.
The current medical practice has become more of a team effort rather than an isolated practice. The current evaluation of patients in the daily practice is essentially performed by medical assessment of the patient in question followed by diagnostic imaging, and when needed and possible the evaluation of tissue for diagnosis with its subsequent assessment of biomarkers and other ancillary tools that play an important role in the evaluation and prognosis. The book herein proposed will exactly provide such assessment focused in the thoracic assessment of patients afflicted with any particular disease of the thorax. Expert clinician in pulmonary medicine will provide the state of the art in the evaluation of such patients, which will provide the most important background in the clinical impression and further assessment of these patients. This assessment in most cases is followed by the evaluation of imaging, which provides a highly important information of not only the exact location of the process but also of the nature of whether is localized, infiltrative, diffuse, bilateral, etc., as well as the possible compromise of other adjacent structures. Such information is crucial as imaging and clinical information will provide a working diagnosis, which ultimately will be defined by the pathological assessment. Therefore, in real practice neither one of these subspecialties works alone or in isolation. On the contrary, each one depends on the other for the final diagnosis and proper management of patients with thoracic diseases. Based on such experience is that the current text will provide in the same text of the needed information that a clinician, radiologist or pathologist will need in order to arrive to the best possible conclusion. The scope of this book is unique in its nature as currently, even though there are several text on either one of those specialties, those publication are strictly on the either radiology, medicine or pathology. Our proposed text will bring all those together in a single text and written by experts in their respective field. This book should be of interest to all of those in the practice of thoracic medicine (radiologist, pulmonologist, pathologists) and any one who in the general practice is confronted with the evaluation of these patients.
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