Biomedicinsk teknik

There are many books written about statistics, some brief, some detailed, some humorous, some colorful, and some quite dry. Each of these texts is designed for a specific audience. Too often, texts about statistics have been rather theoretical and intimidating for those not practicing statistical analysis on a routine basis. Thus, many engineers and scientists, who need to use statistics much more frequently than calculus or differential equations, lack sufficient knowledge of the use of statistics. The audience that is addressed in this text is the university-level biomedical engineering student who needs a bare-bones coverage of the most basic statistical analysis frequently used in biomedical engineering practice. The text introduces students to the essential vocabulary and basic concepts of probability and statistics that are required to perform the numerical summary and statistical analysis used in the biomedical field. This text is considered a starting point for important issues to consider when designing experiments, summarizing data, assuming a probability model for the data, testing hypotheses, and drawing conclusions from sampled data. A student who has completed this text should have sufficient vocabulary to read more advanced texts on statistics and further their knowledge about additional numerical analyses that are used in the biomedical engineering field but are beyond the scope of this text. This book is designed to supplement an undergraduate-level course in applied statistics, specifically in biomedical engineering. Practicing engineers who have not had formal instruction in statistics may also use this text as a simple, brief introduction to statistics used in biomedical engineering. The emphasis is on the application of statistics, the assumptions made in applying the statistical tests, the limitations of these elementary statistical methods, and the errors often committed in using statistical analysis. A number of examples from biomedical engineering research and industry practice are provided to assist the reader in understanding concepts and application. It is beneficial for the reader to have some background in the life sciences and physiology and to be familiar with basic biomedical instrumentation used in the clinical environment. Contents: Introduction / Collecting Data and Experimental Design / Data Summary and Descriptive Statistics / Assuming a Probability Model from the Sample Data / Statistical Inference / Linear Regression and Correlation Analysis / Power Analysis and Sample Size / Just the Beginning / Bibliography

In the past 50 years there has been an explosion of interest in the development of technologies whose end goal is to connect the human brain and/or nervous system directly to computers. Once the subject of science fiction, the technologies necessary to accomplish this goal are rapidly becoming reality. In laboratories around the globe, research is being undertaken to restore function to the physically disabled, to replace areas of the brain damaged by disease or trauma and to augment human abilities. Building neural interfaces and neuro-prosthetics relies on a diverse array of disciplines such as neuroscience, engineering, medicine and microfabrication just to name a few. This book presents a short history of neural interfacing (N.I.) research and introduces the reader to some of the current efforts to develop neural prostheses. The book is intended as an introduction for the college freshman or others wishing to learn more about the field. A resource guide is included for students along with a list of laboratories conducting N.I. research and universities with N.I. related tracks of study.Table of Contents: Neural Interfaces Past and Present / Current Neuroprosthesis Research / Conclusion / Resources for Students

There are five different types of eye movements: saccades, smooth pursuit, vestibular ocular eye movements, optokinetic eye movements, and vergence eye movements. The purpose of this book is focused primarily on mathematical models of the horizontal saccadic eye movement system and the smooth pursuit system, rather than on how visual information is processed. A saccade is a fast eye movement used to acquire a target by placing the image of the target on the fovea. Smooth pursuit is a slow eye movement used to track a target as it moves by keeping the target on the fovea. The vestibular ocular movement is used to keep the eyes on a target during brief head movements. The optokinetic eye movement is a combination of saccadic and slow eye movements that keeps a full-field image stable on the retina during sustained head rotation. Each of these movements is a conjugate eye movement, that is, movements of both eyes together driven by a common neural source. A vergence movement is a non-conjugate eye movement allowing the eyes to track targets as they come closer or farther away. In this book, early models of saccades and smooth pursuit are presented. The smooth pursuit system allows tracking of a slow moving target to maintain its position on the fovea. Models of the smooth pursuit have been developed using systems control theory, all involving a negative feedback control system that includes a time delay, controller and plant in the forward loop, with unity feedback. The oculomotor plant and saccade generator are the basic elements of the saccadic system. The oculomotor plant consists of three muscle pairs and the eyeball. A number of oculomotor plant models are described here beginning with the Westheimer model published in 1954, and up through our 1995 model involving a 4$^{th}$ order oculomotor plant model. The work presented here is not an exhaustive coverage of the field, but focused on the interests of the author. In Part II, a state-of-art model of the saccade system is presented, including a neural network that controls the system. Table of Contents: Introduction / Smooth Pursuit Models / Early Models of the Horizontal Saccadic Eye Movement System / Velocity and Acceleration Estimation / 1995 Linear Homeomorphic Saccadic Eye Movement Model

This book aims to provide vital information about the growing field of bionanotechnology for undergraduate and graduate students, as well as working professionals in various fields. The fundamentals of nanotechnology are covered along with several specific bionanotechnology applications, including nanobioimaging and drug delivery which is a growing $100 billions industry. The uniqueness of the field has been brought out with unparalleled lucidity; a balance between important insight into the synthetic methods of preparing stable nano-structures and medical applications driven focus educates and informs the reader on the impact of this emerging field. Critical examination of potential threats followed by a current global outlook completes the discussion. In short, the book takes you through a journey from fundamentals to frontiers of bionanotechnology so that you can understand and make informed decisions on the impact of bionano on your career and business.

This book presents a discussion of evolving digital technologies, such as smart phones, assisted living, and innovative digitally based services that are helping to deliver quality, cost-effective and widely accessible healthcare for the elderly.

Biomedical Defense Principles to Counter DNA Deep Hacking presents readers with a comprehensive look at the emerging threat of DNA hacking. Dr. Rocky Termanini goes in-depth to uncover the erupting technology being developed by a new generation of savvy bio-hackers who have skills and expertise in biomedical engineering and bioinformatics. The book covers the use of tools such as CRISPR for malicious purposes, which has led agencies such as the U.S. Office of the Director of National Intelligence to add gene editing to its annual list of threats posed by "weapons of mass destruction and proliferation." Readers will learn about the methods and possible effects of bio-hacking attacks, and, in turn the best methods of autonomic and cognitive defense strategies to detect, capture, analyze, and neutralize DNA bio-hacking attacks, including the versatile DNA symmetrical AI Cognitive Defense System (ACDS). DNA bio-hackers plan to destroy, distort and contaminate confidential, healthy DNA records and potentially create corrupted genes for erroneous diagnosis of illnesses, disease genesis and even wrong DNA fingerprinting for criminal forensics investigations.

Biomedical Engineering Modeling of Pancreatic, Respiratory, and Renal Regulatory Systems, and their Medical Assessments addresses the need for biomedical engineering to provide physiological analysis of organ systems and their medical applications to help enable quantitative formulation of physiological systems and defining their functions and dysfunctions, leading to precision diagnostics of diabetes, lung diseases, and kidney failure, often in the form of non-dimensional indices. The book chapters also deal with treatment systems, namely automated insulin infusion systems, hemodialysis, and peritoneal dialysis. The book is formulated to solve many physiological, bioengineering, and medical problems.

Application of Gellan Gum as a Biomedical Polymer details key topics and fundamental aspects of gellan gum and its biomedical applications in drug delivery, proteins and peptides delivery, cell delivery, tissue engineering, wound dressings and enzyme immobilizations in developing high quality products. Sections introduce gellan gum, its source, production and gelation mechanism, discuss biomedical materials, and provides ways it can be used for biomedical applications. The book also examines the used of gellan gum as pharmaceutical excipients for drug delivery. Future developments and challenges round out the book's coverage.With contributions for an international group of experts, this book is a useful reference for scientists, researchers and those in industry engaged in biomedical product development using natural polysaccharides.

Bloom Filter: A Data Structure for Computer Networking, Big Data, Cloud Computing, Internet of Things, Bioinformatics, and Beyond focuses on both the theory and practice of the most emerging areas for Bloom filter application, including Big Data, Cloud Computing, Internet of Things, and Bioinformatics. Sections provide in-depth insights on structure and variants, focus on its role in computer networking, and discuss applications in various research domains, such as Big Data, Cloud Computing, and Bioinformatics. Since its inception, the Bloom Filter has been extensively experimented with and developed to enhance system performance such as web cache. Bloom filter influences many research fields, including Bioinformatics, Internet of Things, computer security, network appliances, Big Data and Cloud Computing.

Dieses Buch fuhrt Sie in die Grundlagen der Biofluidmechanik einWie funktioniert der menschliche Blutkreislauf? Wie arbeiten Mikrozirkulationsvorgange? Mit diesen und vielen weiteren Fragen der Stromungsuntersuchung beschaftigt sich die Biofluidmechanik. Dieses Buch gewahrt ihnen interessante Einblicke in die Grundlagen der Biofluidmechanik.Die Biofluidmechanik ist eine thematisch sehr breit gestaffelte Wissenschaft. Sie erforscht die Gesetzmaigkeiten der Bewegung, des Kraftegleichgewichtes und der Stromungstechnik von Fluiden. Hierzu gehoren unter anderem:* Atmung* Blutkreislauf* Mikrozirkulationsvorgange* Lymphstromungen* Kunstliche Gefaersatze* Gefaprothesen aus verschiedenen Materialien* Kunstliche Herzklappen* Urologische Messungen* Kunstliche Harnleiter* Blutrheologie* Transport durch Membranen* Bewegung geladener Partikel* Ionen in Losungen* Vibrationen* Wellenfortpflanzung und SchockwellenWichtiges Grundlagenwissen der Biofluidmechanik in einem Buch In seinem Buch gibt der Autor einen ausfuhrlichen Uberblick uber die Grundlagen der Biofluidmechanik und stellt die folgenden Themen detailliert vor:* Einleitung in die Biofluidmechanik* Physikalische Grundlagen von Fluiden* Rheologische Grundlagen* Biofluide (Korperflussigkeiten) in Menschen und Tieren* Grundlegende theoretische Fluid- bzw. hamodynamische Betrachtungen* Medizinische Grundlagen, menschliches Kreislaufsystem, Blutgefae, Herz, Lungenmechanik und Atmung* Besonderheiten und Messmethoden der Biofluidmechanik* Anwendungen und Beispiele in Modellen, diagnostische und therapeutische BedeutungAufgrund des hohen Praxisbezugs ist dieses Buch uber die Biofluidmechanik nicht nur fur Studenten, sondern auch fur Beschaftigte in Gesundheitsforschung und Medizin ein wichtiges und hilfreiches Grundlagenwerk. 

This first book on high-speed atomic force microscopy (HS-AFM) is intended for students and biologists who want to use HS-AFM in their research. It provides straightforward explanations of the principle and techniques of AFM and HS-AFM. Numerous examples of HS-AFM studies on proteins demonstrate how to apply this new form of microscopy to specific biological problems. Several precautions for successful imaging and the preparation of cantilever tips and substrate surfaces will greatly benefit first-time users of HS-AFM. In turn, the instrumentation techniques detailed in Chapter 4 can be skipped, but will be useful for engineers and scientists who want to develop the next generation of high-speed scanning probe microscopes for biology.The book is intended to facilitate the first-time use of this new technique, and to inspire students and researchers to tackle their own specific biological problems by directly observing dynamic events occurring in the nanoscopic world. Microscopy in biology has recently entered a new era with the advent of high-speed atomic force microscopy (HS-AFM). Unlike optical microscopy, electron microscopy, and conventional slow AFM, it allows us to directly observe biological molecules in physiological environments. Molecular "e;movies"e; created using HS-AFM can directly reveal how molecules behave and operate, without the need for subsequent complex analyses and roundabout interpretations. It also allows us to directly monitor morphological change in live cells, and dynamic molecular events occurring on the surfaces of living bacteria and intracellular organelles. As HS-AFM instruments were recently commercialized, in the near future HS-AFM is expected to become a common tool in biology, and will enhance and accelerate our understanding of biological phenomena.

Wearable Systems Based Gait Monitoring and Analysis provides a thorough overview of wearable gait monitoring techniques and their use in health analysis. The text starts with an examination of the relationship between the human body's physical condition and gait, and then introduces and explains nine mainstream sensing mechanisms, including piezoresistive, resistive, capacitive, piezoelectric, inductive, optical, air pressure, EMG and IMU-based architectures. Gait sensor design considerations in terms of geometry and deployment are also introduced. Diverse processing algorithms for manipulating sensors outputs to transform raw data to understandable gait features are discussed. Furthermore, gait analysis-based health monitoring demonstrations are given at the end of this book, including both medical and occupational applications. The book will enable students of biomedical engineering, electrical engineering, signal processing, and ergonomics and practitioners to understand the medical and occupational applications of engineering-based gait analysis and falling injury prevention methods.

This book begins with an introduction of nanobiotechnology, followed by biosyntheses of AgNPs, development of silver/chitosan (Ag/CS) polymer nanocomposites, synthesis of silver/chitosan-g-poly acrylamide (Ag/CS-g-PAAm) nanocomposite hydrogel and silver/chitosan/poly vinyl chloride (Ag/CS/PVC) blend. Finally, it presents novel bioengineering of polyfunctional metallic nanostructures other than Ag, emphasizing biomass utilization and value-added conversion over an extended span, including life cycle assessment of the synthesized nanostructures.Features:Includes prospective cost effective, eco-friendly, and safe nanomaterials, synthesized through facile pathsCovers the synergistic effect of phytochemicals and nano-Ag antimicrobial agents from an antiviral perspectiveIncludes surface coating systems and super absorbent materials for biomedical purposesExamines nanobiotechnological applications for generating nanoalloys with synchronized nanostructural arrangement of alkaline earth metals and nanoscale dots of transition metalsExplores the life cycle assessment of synthesized nanomaterialsThis book aims at researchers and graduate students in biomaterials, chemical engineering, green chemistry, nanomaterials, and biotechnology.

The book, Nanosensors for Futuristic Smart and Intelligent Healthcare Systems, presents a treatise on nanosensors technology including wearables, implantable devices and wireless tools. The recent pandemic (COVID-19) has changed the behaviour of people towards diagnosis of infectious diseases and monitoring remote patient health status in real-time. The main focus of this book is the basic concepts of nanomaterials and sensing paradigms for medical devices based on nanosensor technology. The book will be valuable to researchers, engineers and scientists interested in the field of healthcare for monitoring health status in real-time.

From everyday applications to the rise of automation, devices have become ubiquitous. Specific materials are employed in specific devices because of their particular properties, including electrical, thermal, magnetic, mechanical, ferroelectric, and piezoelectric. Materials for Devices discusses materials selection for optimal application and highlights current materials developments in gas sensors, optical devices, mechanoelectrical devices, and medical and biological devices.Explains how to select the right material for the right deviceIncludes 2D materials, thin films, smart piezoelectric films, and morePresents details on organic solar cellsDescribes thin films in sensors, actuators, and LEDsCovers thin films and elastic polymers in biomedical devicesDiscusses growth and characterization of intrinsic magnetic topological insulatorsThis work is aimed at researchers, technologists, and advanced students in materials and electrical engineering and related fields who are interested in developing sensors or devices.

Discusses various applications of ML in engineering fields and the use of ML algorithms in solving challenging engineering problems ranging from biomedical to manufacturing and industrial. Through numerous case studies, it will assist researchers and practitioners in selecting the correct options and strategies for managing organizational tasks.

Oral tissue engineering involves the study of current approaches for in vitro regeneration of soft and hard tissues located into the oral cavity. The objective of this book is to highlight current progress in tissue engineering for various dental hard/soft tissues including enamel, dentin, pulp, alveolar bone, etc.

This book acts as a primer for radiographers upon performing computed tomography (CT) examinations. The focus resides in radiation physics, radiobiology, anatomy, imaging protocols and image evaluation. It seeks to provide readers insight into the practical and innovative approaches within CT, backed up with key literature and examples in practice. Recent innovations and the importance of new technology to acquire enhanced quality remain a focal point. These are essential in understanding the importance of dose optimization, patient anatomy and common pathology observed. Patient care will remain central in this book, supported with a dedicated chapter discussing effective communication, patient education, informed consent, coupled with the assessment of laboratory results and vital signs. The editors draw from recent publications and clinical expertise, supported with the growing trend of technological advances utilized within the CT environment. Critically, this volume focuses on the role of CT for an array of audiences but, more specifically, undergraduate and postgraduate radiographers worldwide.

The reference text covers computational intelligence, artificial intelligence, cognitive systems, industrial IoT, and industry 4.0. It will be an ideal reference text for graduate students, professional and academic researchers in the fields of electrical engineering, electronics and communication engineering, and computer science.