Biomedicinsk teknik

Dive into the intricate realm of osteoporosis through the lens of biomechanics with Biomechanical Insights into Osteoporosis. This pioneering volume offers a comprehensive exploration of this debilitating condition, providing an in-depth understanding of its biomechanical foundations and implications. Osteoporosis, characterized by reduced bone mineral density and heightened susceptibility to fractures, stands as a global health challenge. This book brings together leading experts in the field, who rigorously analyze the multifaceted aspects of osteoporosis, offering invaluable knowledge for researchers, clinicians, and students alike.Key Highlights:¿Biomechanical Foundations: Gain profound insights into the biomechanical basis of bone fractures and fracture osteosynthesis in small animals. Explore the fundamental principles that shape our understanding of osteoporotic biomechanics. ¿Non-Glucocorticoid Drug-Induced Osteoporosis: Investigate the mechanisms, risk factors, and therapeutic approaches for osteoporosis induced by medications other than glucocorticoids. ¿Vascular Remodeling and Bone Destruction: Discover the common pathogenetic links between vascular remodeling and bone tissue destruction in postmenopausal women with arterial hypertension. This holistic perspective illuminates bone health dynamics. ¿Genetic Targets and Future Directions: Explore promising genetic targets that have the potential to revolutionize osteoporosis treatment. Get a glimpse into the future of research and treatment strategies. ¿Biomarkers and Metabolism: Delve into the latest research progress surrounding bone mineral density and bone metabolism biomarkers, offering valuable insights into diagnostics and monitoring. ¿Impact of Diseases and Medical Treatments: Understand the intricate interplay between diseases and medical treatments on bone mineral density. Gain a comprehensive understanding of how various factors influence skeletal health.This book represents a significant milestone in deciphering the complexities of osteoporosis from a biomechanical perspective. Join us in this scientific journey to explore the fascinating facets of osteoporosis. Biomechanical Insights into Osteoporosis is an essential resource for anyone seeking a deeper understanding of this critical health issue and the biomechanical aspects that underlie it.

This book provides a thorough overview of cutting-edge research on electronics applications relevant to industry, the environment, and society at large. It covers a broad spectrum of application domains, from automotive to space and from health to security, while devoting special attention to the use of embedded devices and sensors for imaging, communication, and control. The book is based on the 2023 ApplePies Conference, held in Genoa, Italy, in September 2023, which brought together researchers and stakeholders to consider the most significant current trends in the field of applied electronics and to debate visions for the future. Areas addressed by the conference included information communication technology; biotechnology and biomedical imaging; space; secure, clean, and efficient energy; the environment; and smart, green, and integrated transport. As electronics technology continues to develop apace, constantly meeting previously unthinkable targets, further attention needs tobe directed toward the electronics applications and the development of systems that facilitate human activities. This book, written by industrial and academic professionals, represents a valuable contribution in this endeavor.

This volume ¿Cell Engineerring 11 - Biopharmaceutical Manufacturing: Progress, Trends and Challenges¿ is a source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation.The book comprises contributions of experts from academia and industry active in the field of cell culture development for the production of recombinant proteins, cell therapy and gene therapy, with consideration of Digital Twin¿s and facility design. The knowledge and expertise of the authors cover disciplines like cell biology, engineering, biotechnology and biomedical sciences. Inevitably, some omissions will occur in the test, but the authors have sought to avoid duplications by extensive cross-referencing to chapters in other volumes of this series and elsewhere. We hope the volume provides a useful compendium of techniques for scientists in industrial and research laboratories active in this field.

This book gathers the proceedings of the 8th International Conference on Advancements of Medicine and Health Care through Technology, MEDITECH 2022, held virtually on 20¿22 October 2022, from Cluj-Napoca, Romania. It reports on both theoretical and practical developments in biomedical imaging and image processing, health technology, technologies for education, and biomedical signal processing and medical devices, measurements and instrumentation. Both the conference and the realization of this book were supported by the Romanian National Society for Medical Engineering and Biological Technology (SNIMTB).

This book showcases recent trends in brain-computer interface development. It highlights fascinating results in areas such as language decoding, spinal cord stimulation to enable gait and to restore hand functions. The contributions are based on the 12 nominated brain-computer interface projects of the BCI Award 2022. Every year an international jury selects the most innovate BCI projects and nominates 12 projects before selecting the 1st, 2nd and 3rd place winners. In the book, each project is described in detail by the team of scientists behind it, and the editors provide a concluding discussion of the highlights and overall progress in the field.

Human history is filled with inventions and other innovations that resulted in a significant and lasting change in our civilization¿s course of development. From gasoline-powered vehicles to transistor-based electronics or jet airplanes, things we now take for granted often appeared suddenly and unexpectedly. Yet after their introduction, our world changed forever. Over the past two decades, artificial intelligence (AI) and machine learning (ML) have been stealthily increasing their presence in our everyday lives. This ¿randomly systematic¿ adoption process is exposing humanity to something we never previously directly faced: an intelligence that may (and likely will) exceed our own. Despite this, most people are not fully aware of current (and future) benefits, limitations, and threats related to AI/ML. Within health care, there is little awareness of what AI/ML is capable of and how these new capabilities are being implemented or utilized. It is this current state that serves as our ¿starting point¿ in the emerging debate on AI/ML in medicine and surgery, including its integration, projected influence, and many other considerations that are not that different from other past technology adoption paradigms. This book discusses both current trends and future developments in AI and ML across health care.

Chitosan-Based Nanoparticles for Biomedical Applications explores the use of chitosan-based nanoparticles as a sustainable solution for the development of improved therapeutic and diagnostic techniques. A range of biomedical applications is reviewed, including treatment against highly resistant bacteria and parasites; tissue regeneration; drug delivery, and more. Moreover, the application of chitosan-based nanoparticles for the effective delivery of hormones, vaccines, phytochemicals, nutraceuticals, and their application in immobilization of enzymes is also discussed in detail. This book provides a state-of-the-art overview for materials scientists, pharmaceutical scientists, and researchers with an interest in the development of novel materials for therapeutics.

Intelligent Biomedical Technologies and Applications for Healthcare 5.0, Volume Sixteen covers artificial health intelligence, biomedical image analysis, 5G, the Internet of Medical Things, intelligent healthcare systems, and extended health intelligence (EHI). This volume contains four sections. The focus of the first section is health data analytics and applications. The second section covers research on information exchange and knowledge sharing. The third section is on the Internet of Things (IoT) and the Internet of Everything (IoE)-based solutions. The final section focuses on the implementation, assessment, adoption, and management of healthcare informatics solutions. This new volume in the Advances in Ubiquitous Sensing Applications for Healthcare series focuses on innovative methods in the healthcare industry and will be useful for biomedical engineers, researchers, and students working in interdisciplinary fields of research. This volume bridges these newly developing technologies and the medical community in the rapidly developing healthcare world, introducing them to modern healthcare advances such as EHI and Smart Healthcare Systems.

Biomechatronics is rapidly becoming one of the most influential and innovative research directions defining the 21st century. The second edition Biomechatronics provides a complete and up-to-date account of this advanced subject at the university textbook level. This new edition introduces two new chapters - Animals Biomechatronics and Plants Biomechatronics - highlighting the importance of the rapidly growing world population and associated challenges with food production. Each chapter is co-authored by top experts led by Professor Marko B. Popovic, researcher and educator at the forefront of advancements in this fascinating field. Starting with an introduction to the historical background of Biomechatronics, this book covers recent breakthroughs in artificial organs and tissues, prosthetic limbs, neural interfaces, orthotic systems, wearable systems for physical augmentation, physical therapy and rehabilitation, robotic surgery, natural and synthetic actuators, sensors, and control systems. A number of practice prompts and solutions are provided at the end of the book. The second edition of Biomechatronics is a result of dedicated work of a team of more than 30 contributors from all across the globe including top researchers and educators in the United States (Popovic, Lamkin-Kennard, Herr, Sinyukov, Troy, Goodworth, Johnson, Kaipa, Onal, Bowers, Djuric, Fischer, Ji, Jovanovic, Luo, Padir, Tetreault), Japan (Tashiro, Iraminda, Ohta, Terasawa), Sweden (Boyraz), Turkey (Arslan, Karabulut, Ortes), Germany (Beckerle and Wiliwacher), New Zealand (Liarokapis), Switzerland (Dobrev), and Serbia (Lazarevic).

Predictive Analytics using MATLAB(R) for Biomedical Applications is a comprehensive and practical guide for biomedical engineers, data scientists, and researchers on how to use predictive analytics techniques in MATLAB(R) for solving real-world biomedical problems. The book offers a technical overview of various predictive analytics methods and covers the utilization of MATLAB(R) for implementing these techniques. It includes several case studies that demonstrate how predictive analytics can be applied to real-world biomedical problems, such as predicting disease progression, analyzing medical imaging data, and optimizing treatment outcomes.With a plethora of examples and exercises, this book is the ultimate tool for reinforcing one’s knowledge and skills.

Joint Replacement in the Human Body provides a comprehensive exploration of artificial joint designs. The book's primary focus is to introduce readers to the diverse landscape of artificial joint technologies while offering insights into their historical development. This book is divided into three sections, each addressing specific aspects of joint replacements. The first section delves into artificial joints of the lower limb, including the hip, knee, and ankle. In the subsequent section, the book explores upper limb replacements, covering joints such as the shoulder, elbow, wrist, finger, and thumb.The third section tackles broader themes like biotribology, regulatory aspects of joint replacements, examines noteworthy case studies like metal-on-metal hips, and addresses joint replacements not easily categorized in the previous sections, such as spinal total disc replacements. This book offers a critical assessment of the diverse and evolving design concepts currently in use, ranging from established metal-on-polymer joints to innovative biomimetic solutions. This book is designed to swiftly equip readers with a deep understanding of contemporary joint replacements and the immediate and long-term challenges they present.

Nanozymes: Approachable Bio-applications provides an in-depth overview of nanozymes, with a special focus on nanozymes synthesis and their various applications in biological sciences. The book starts with introductory chapters exploring the enzymatic mechanism of nanozymes and providing the concept of engineering to surface modification to achieve enhanced nanozymatic properties. Subsequent chapters focus on the application of nanozymes in many different fields, including biomedical science, agriculture, environmental science and more.This work is an important reference source for worldwide materials scientists and researchers interested on the resent developments, challenges, and future directions of nanozymes research.

Generative Artificial Intelligence is rapidly advancing with many state-of-the-art performances on computer vision, speech processing, and natural language processing tasks. Generative adversarial networks and neural diffusion models can generate high-quality synthetic images of human faces, artworks, and coherent essays on different topics. Generative models are also transforming Medical Artificial Intelligence, given their potential to learn complex features from medical imaging and healthcare data. Hence, computer-aided diagnosis and healthcare are benefiting from Medical Artificial Intelligence and Generative Artificial Intelligence. This book presents the recent advances in generative models for Medical Artificial Intelligence. It covers many applications of generative models for medical image data, including volumetric medical image segmentation, data augmentation, MRI reconstruction, and modeling of spatiotemporal medical data. This book highlights the recent advancements in Generative Artificial Intelligence for medical and healthcare applications, using medical imaging and clinical and electronic health records data. Furthermore, the book comprehensively presents the concepts and applications of deep learning-based artificial intelligence methods, such as generative adversarial networks, convolutional neural networks, and vision transformers. It also presents a quantitative and qualitative analysis of data augmentation and synthesis performances of Generative Artificial Intelligence models. This book is the result of the collaborative efforts and hard work of many minds who contributed to it and illuminated the vast landscape of Medical Artificial Intelligence. The book is suitable for reading by computer science researchers, medical professionals, healthcare informatics, and medical imaging researchers interested in understanding the potential of artificial intelligence in healthcare. It serves as a compass for navigating the artificial intelligence-driven healthcare landscape.

This book provides an introduction to next-generation applications and technologies for improving diagnostic accuracy and prediction of treatment outcomes in dentistry through the use of artificial intelligence (AI) and machine learning (ML). The authors attempt to bridge the gap between dental research and global health outcomes, as well as provide a comprehensive guide to general and clinical aspects of dental and oral health issues and the etiology, prevalence, assessment, and management of these conditions. This book combines engineering applications and medical healthcare and will be an important reference for researchers, biomedical engineers, dental students, and dental practitioners. 

Biomaterials and Stem Cell Therapies for Biomedical Applications discusses the current research concepts and emerging technologies in the fields of biomaterials and tissue engineering. Divided into four distinct sections, the book explores these state-of-the art technologies, opening with a description of stem cell technologies for biomedical applications before exploring biomaterials for biomedical applications, combinational approaches using stem cells and biomaterials, and finally, nanomedicine approaches for tissue regeneration. Topics include wound healing, tissue engineering, regenerative biomaterials, and stem cell treatments for wound healing and tissue regeneration. This concise and informative volume presents the latest developments in a highly informative and easy-to-read style.

This book describes a new strategy for rehabilitation from injury and/or disease using Crucial Event Therapy. Recent studies have shown that individuals can recuperate more rapidly from surgery and other invasive procedures intended to correct the negative effects of disease or injury through the use of life support systems that operate at the body's natural biofrequencies. The same observation has been clinically shown to reverse the degenerative effects of neurodegenerative diseases such as Parkinson¿s and Alzheimer's Disease.Crucial Event Therapy describes medicine as the operational control of the functions of the human body treated as a network-of-networks, with 1/f-variable crucial events coding the dynamic states of health and disease through information flow within a network and information exchange between biomedical networks. A new way of thinking based on the statistics of Cortical Events is presented and the relevant literature is suitably referenced. This is anideal book for biophysicists and data scientists seeking to understand the connection of complexity measures for the study of consciousness with the clinical aspects of designing a rehabilitation strategy.

Fundamentals and Biomedical Applications of Chitosan Nanoparticles holistically covers the development and application of chitosan nanoparticles, providing an accessible and interdisciplinary resource for both those new to the field and those who wish to deepen their knowledge. The book begins with an introduction to synthesis methods, fundamental chemistry, characterization, and surface functionalization of chitosan nanoparticles, guiding the reader through each stage of development. A wide range of biomedical applications are explored, from vaccine delivery, tumor targeting, tissue engineering, and wound healing and antimicrobial therapy. This will be a helpful guide for postgraduate students and researchers who are starting out in this field, as well as established researchers in the fields of materials science, nanotechnology, materials chemistry, and bioscience.

This book aims to highlight the latest achievements in the use of AI and multimodal artificial intelligence in biomedicine and healthcare. Multimodal AI is a relatively new concept in AI, in which different types of data (e.g. text, image, video, audio, and numerical data) are collected, integrated, and processed through a series of intelligence processing algorithms to improve performance. The edited volume contains selected papers presented at the 2022 Health Intelligence workshop and the associated Data Hackathon/Challenge, co-located with the Thirty-Sixth Association for the Advancement of Artificial Intelligence (AAAI) conference, and presents an overview of the issues, challenges, and potentials in the field, along with new research results. This book provides information for researchers, students, industry professionals, clinicians, and public health agencies interested in the applications of AI and Multimodal AI in public health and medicine.

This book covers a variety of advanced communications technologies that can be used to analyze medical data and can be used to diagnose diseases in clinic centers. The book is a primer of methods for medicine, providing an overview of explainable artificial intelligence (AI) techniques that can be applied in different medical challenges. The authors discuss how to select and apply the proper technology depending on the provided data and the analysis desired. Because a variety of data can be used in the medical field, the book explains how to deal with challenges connected with each type. A number of scenarios are introduced that can happen in real-time environments, with each pared with a type of machine learning that can be used to solve it.

Clinical trials are research studies performed in people that are aimed at evaluating a medical device, drug, or surgical or behavioral intervention. They are the primary way that researchers find out if a new treatment, like a new drug or medical device (e. g., a neuroendovascular device) is safe and effective for patients. A clinical trial is used to confirm if a new treatment is more effective and/or has less harmful side effects than the standard treatment. Other clinical trials test methods of early disease detection, sometimes before there are any symptoms. Still, others test methods to prevent health problems. A clinical trial may also look at how to improve the quality of life in those individuals with a life-threatening disease or chronic health problem. Clinical trials sometimes even study the role of caregivers or support groups. Therefore, clinical trials are very important in the development of medicine. A good clinical trial can influence therapeutic modality and even transform our healthcare work. This book provides a comprehensive review of clinical trials.

Biomaterials play a crucial role in the field of biomedical engineering, offering innovative solutions for a wide range of medical applications. From artificial organs to drug delivery systems, biomaterials have revolutionized healthcare and continue to shape the future of medicine. In this subchapter, we will delve into the fundamental aspects of biomaterials, providing students of biomedical engineering with a comprehensive understanding of this exciting field.Firstly, it is important to define what biomaterials are. Simply put, biomaterials are materials that interact with biological systems, either as a whole or at the molecular level. These materials can be natural, such as collagen or silk, or synthetic, such as polymers or ceramics. Understanding the properties and characteristics of different biomaterials is crucial for designing and developing successful biomedical devices and implants.We will explore the various types of biomaterials commonly used in biomedical engineering, including metals, ceramics, polymers, and composites. Each material has unique properties and advantages, which make them suitable for specific applications. For example, metals like titanium are commonly used for orthopedic implants due to their excellent mechanical properties, biocompatibility, and corrosion resistance.Furthermore, we will discuss the interactions between biomaterials and the human body. When a biomaterial is implanted or used in a medical device, it interacts with the surrounding biological environment, which can elicit various responses. These interactions can be classified into four categories: mechanical, chemical, physical, and biological. Understanding these interactions is crucial for predicting the behavior of biomaterials inside the body and ensuring their safe and effective use.Additionally, we will examine the biocompatibility of biomaterials, which refers to their ability to perform their desired function without causing any adverse reactions in the body. Biocompatibility is a complex concept that involves multiple factors such as cytotoxicity, immunogenicity, and hemocompatibility. We will explore the various tests and standards used to evaluate the biocompatibility of biomaterials, ensuring that students have a comprehensive understanding of this critical aspect.Finally, we will discuss the future trends and advancements in biomaterials. From tissue engineering to smart biomaterials, the field is rapidly evolving, opening up new possibilities for biomedical engineering. Understanding these trends will not only enhance students' knowledge but also inspire them to contribute to the future of biomaterials and healthcare.

This comprehensive guide invites nations worldwide to embark on a transformative journey, implementing independent third-party verification systems that ensure medical devices comply with both international and national regulations. Prepare to be captivated as we delve into the intricate processes, unveil essential procedures, and illuminate the paramount importance of establishing traceability for medical device measurements.Imagine a world where medical devices undergo rigorous independent safety and performance verification, guaranteeing the utmost reliability for patient diagnoses and treatment. This book takes you on a compelling exploration of precisely that vision. Focusing on cutting-edge diagnostic and therapeutic devices, it captures the very essence of the latest international directives and regulations, ensuring you stay ahead of the curve.This new edition goes beyond the conventional, delving into the realms of innovation and progress. Unveiling in-depth maintenance regimes within healthcare institutions, we provide you with invaluable insights into post-market surveillance. As the world embraces the transformative potential of artificial intelligence, we pave the way for evidence-based management of medical device maintenance¿a concept poised to reshape the healthcare landscape.Imagine a future where medical devices are seamlessly integrated into the legal metrology system, while fully operational national laboratories for medical device inspection set new standards of excellence. This book vividly illustrates how such a powerful union can elevate the reliability of medical devices in diagnosis and patient care. Brace yourself for a paradigm shift that not only enhances efficacy but also leads to significant cost reductions within your country's healthcare system.Join us on this extraordinary journey as we unveil the untapped potential of medical device inspection. With our innovative approach and unrivaled expertise, together we can revolutionize healthcare, transforming the lives of countless patients worldwide. Get ready to be inspired, informed, and empowered¿welcome to the future of healthcare!

This book describes current and potential use of artificial intelligence and computational intelligence techniques in biomedicine and other application areas. Medical applications range from general diagnostics to processing of X-ray images to e-medicine-related privacy issues.Medical community understandably prefers methods that have been successful other on other application areas, where possible mistakes are not that critical. This book describes many promising methods related to deep learning, fuzzy techniques, knowledge graphs, and quantum computing. It also describes the results of testing these new methods in communication networks, education, environmental studies, food industry, retail industry, transportation engineering, and many other areas. This book helps practitioners and researchers to learn more about computational intelligence methods and their biomedical applications-and to further develop this important research direction.