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From one of the world's great science writers and biologists: a book that reflects on the vast arc of evolutionary history and what it tells us about life on earth.How much do we really know about our past?For centuries, we have yearned to learn more about our ancestors and piece together the story of how we came to be. But language can only record so much. And fossils can be even harder to decipher. We are left groping in the dark, forced to speculate and reconstruct ways of life based on fragments of information.But what if there was a better way?In The Genetic Book of the Dead, Richard Dawkins explores the untapped potential of DNA to transform and transcend our understanding of evolution. In the future, a zoologist presented with a hitherto unknown animal will be able to read its body and its genes as detailed descriptions of the world its ancestors inhabited. This 'book of the dead' would uncover the remarkable ways in which animals have overcome obstacles, adapted to their environments and, again and again, developed remarkably similar ways of finding solutions to life's problems. What biologists call ?convergent evolution', the way in which species separated by vast stretches of time have evolved surprisingly recognisable forms and functions, is one of the most powerful and least understood forces driving life on earth.From the bestselling author of The Selfish Gene comes a revolutionary book that unlocks the door to a past more vivid, nuanced and fascinating than anything we have ever seen.
This book highlights the interrelation between cell cycle regulators and breast cancer phenotypes. It reviews the roles of Cyclin-Dependent Kinases (CDK) in driving cell cycle progression, cell cycle checkpoints and dysregulation in breast cancer. It also examines the prognostic significance of CDKs in breast cancer. and CDK inhibitors for the treatment of metastatic breast cancer. Further, the book discusses the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation in breast cancer. Additionally, it examines the role of immunogenic effects of CDK inhibitors, the mechanism of resistance and the current clinical trials in breast cancer treatment. Towards the end, the book explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer. This book is a comprehensive yet concise resource for oncologists and researchers interested in exploring the therapeutic potential of Cyclin-Dependent Kinases in breast cancer.¿
Though forensic genetic technologies are upheld as important tools of justice the development of these technologies has been accomplished through the ongoing genetic servitude of Indigenous Peoples. Forensic Colonialism explores how these controversial methods serve only privileged populations, and keep others exploited and criminalized.
Exploring plant genetic resources is crucial in a time when food security has been a critical topic worldwide due to crop shortages and the impact of climate change.This new book, Plant Genetic Resources for the 21st Century: The OMICS Era, presents the practical advancements in genomics, epigenetics, metabolomics, and phenomics from the point of view of researchers and scientists working in the field of genebanks, genetics resources, and germplasm for enabling plant breeding and adaptation to a changing climate. The book highlights the importance of genebanks as centers of innovation for crop and forage improvement and discusses database solutions for genebanks and germplasm collections.The book first looks at plant genetic resources and their values and goes on to investigate several genomic technologies for plant improvement, conservation, and better adaptation to changing climates. Major crops such as wheat and barley are discussed with genomic approaches for diversity and resilience to drought and other adverse conditions. Other omics techniques discussed include phenomics for the improvement of crop adaptation, metabolomics research for germplasm improvement and adaptation, and more.This volume will be valuable for researchers who are presently working in or with genebanks and genetic resources, primarily for trait or allele discovery and germplasm improvement. Most chapters in the book can also be used as teaching material at the undergraduate and postgraduate levels.
This volume brings together the world's leading experts on disgust to fully explore this understudied behavior. Disgust is unique among emotions. It is, at once, perhaps the most ¿basic¿ and visceral of feelings while also being profoundly shaped by learning and culture. Evident from the earliest months of life, disgust influences individual behavior and shapes societies across political, social, economic, legal, ecological, and health contexts. As an emotion that evolved to prevent our eating contaminated foods, disgust is now known to motivate wider behaviors, social processes, and customs. On a global scale, disgust finds a place in population health initiatives, from hand hygiene to tobacco warning labels, and may underlie aversions to globalization and other progressive agendas, such as those regarding sustainable consumption and gay marriage.This comprehensive work provides cutting¿edge, timely, and succinct theoretical and empirical contributions illustrating thebreadth, rigor, relevance, and increasing maturity of disgust research to modern life. It is relevant to a wide range of psychological research and is particularly important to behavior viewed through an evolutionary lens, As such, it will stimulate further research and clinical applications that allow for a broader conceptualization of human behavior.The reader will find:Succinct and accessible summaries of key perspectivesHighlights of new scientific developmentsA rich blend of theoretical and empirical chapters
Genomics, Transcriptomics, Proteomics and Metabolomics of Crop Plants presents current operational methods applied to model crop plants. Including subcellular organelles, DNA fingerprinting and barcoding, sRNA, gene expression, rhizosphere engineering, marker assisted and 5G breeding, plant-microorganism interactions, stress signaling and responses, the book highlights important factors that are often overlooked and explores the latest research. The book also explores cutting-edge approaches for immediate application in new research such as OMICS, genome-wide transcriptome profiling, bioinformatics and database, DNA fingerprinting and barcoding, sRNA, gene expression, genome editing, diagnostics, rhizosphere engineering, marker assisted and 5G breeding, crop plant-microorganism interactions, stress signaling and responses. Additionally, the book describes opportunities to manipulate crop plants genetic and metabolic systems, while also exploring the related bioethical and biosafety issues. These topics are chosen and covered in detail to fill the gap in this understanding of crop molecular biology.
Genetics: Analysis and Principles is a one-semester, introductory genetics textbook that takes an experimental approach to understanding genetics. By weaving one or two experiments into the narrative of each chapter, students can simultaneously explore the scientific method and understand the genetic principles that have been learned from these experiments. The pedagogy of Genetics: Analysis & Principles has been designed to foster student learning. Instead of being a collection of facts and figures,this text is intended to be an engaging and motivating textbook in which formative assessment allows students to move ahead and learn the material in a productive way.
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