Introductory Adaptive Trial Designs - Mark Chang - Bog

Taking a learning-by-doing approach, this tutorial-style book helps newcomers quickly and easily grasp the essence of adaptive designs as well as the foundations of adaptive design methods. It reduces the mathematics to a minimum and makes the material as practical as possible. The author includes R functions that enable readers to better understand the algorithms and customize the designs to meet their needs. For those with no R experience, an appendix provides a 30-minute R tutorial.