Postoperative antibiotic therapy and acute cholecystitis - Leila Khennaf - Bog

The prognosis of cholecystitis depends on the speed of management. Early laparoscopy is the treatment of choice. There is still the problem of postoperative antibiotic therapy? This is a prospective, single-centre, randomised study. 176 patients with 88 in each arm. Pathology: mild to moderately severe acute cholecystitis that could benefit from early cholecystectomy. All patients received preoperative dual antibiotic therapy. Prior to surgery, the patients were randomly divided into two groups. One group continued to receive the same antibiotic therapy preoperatively, and 5 days later the other group received no further treatment. Mortality was zero in both arms. The postoperative infection rate was 4.5% in the group without antibiotics and 3.4% in the group with antibiotics. Clavien score, identical in both groups. The absence of antibiotics does not mean infection, sometimes even prophylactic antibiotics do not protect against infection. Let's save drugs, health has no price, but it has a cost!