Immunologi

Antimicrobial resistance (AMR) is one of the deadliest threats to global public health. This book focuses on dynamics in the landscape of AMR while informing about the latest technologies and strategies to mitigate it. The menace of AMR in different niches, routes of penetration across various domains, socio-economic impact, and the need for a 'One Health' approach in mitigating AMR has been emphasized. Factors involved in AMR, underlying mechanisms, and pharmacometrics in developing antimicrobials are highlighted. Emphasis is given to emerging technologies that are sustainable, scalable, and applicable to the global community, such as big data analytics, bioactive agents, phage therapy, and nanotechnology. The book also explores current and alternative treatment strategies to combat AMR, emphasizing the use of nanoparticles to target pathogens and as a viable alternative to antibiotics.

This new collection features the most up-to-date essential protocols that are currently being used to study the immune synapse. Beginning with methods for making biophysical measurements, the volume continues by covering the cell biology of synapses, methods for advanced substrate engineering, mechanobiology topics, new technologies to describe and manipulate synaptic components, as well as methods related to sites of action and immunotherapy. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and fully updated, The Immune Synapse: Methods and Protocols, Second Edition serves as an ideal practical guide for researchers working in this dynamic field. Chapters 5, 11,18, 27, 30, and 32 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

We're told that we need to exercise to stay healthy, but we're not told HOW to exercise. We're certainly not told how to exercise with an autoimmune condition. This is the definitive book you need to help you understand and support your body when exercising with an autoimmune condition.Here, Zoe tells us of her own health journey, whilst exploring the benefits of exercise for someone with an autoimmune condition and how you can get onto a plan that suits your needs. She uses case studies, experts and her own research to explore:- the benefits of exercising with a chronic condition- the barriers to exercising with a chronic condition and how to overcome them- how to keep motivation high when exhausted - which exercises you should do (complete with illustrations)- how to adapt your exercises depending on your condition- how to get into the right mindset with exerciseZoe teaches with compassion and understanding that is unique in this field and brings to market a guide that covers all aspects of exercising with chronic conditions, including simple, clear practices that you can put into action and meld into part of your balanced lifestyle programme.

Meticulously reviewed and updated for today's medical students, Basic Immunology, 7th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume has been fully revised to include recent important advances in our understanding and knowledge of the immune system. A student favorite through six outstanding editions, this new edition uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases-all designed to help you master this complex topic in the most efficient, effective manner possible. Emphasizes clinical aspects of immunology, including disease pathogenesis, the development of novel therapies based on basic science, and an appendix of clinical cases for real-world application.  Contains new and expanded content on pandemics, COVID-19, and herd immunity; resistance and susceptibility to COVID-19; RNA vaccines and hybrid viral vaccines; tumor immunotherapy; innate immune responses to viruses; mechanisms of immunologic tolerance; and immunotherapy for autoimmune, allergic, and other inflammatory diseases, and cancer.  Provides unrivalled instruction from an expert author team, all of whom are experienced teachers, course directors, and lecturers.  Features a highly readable writing style and practical organization, now with fully revised content and updated images to cover new information and improve reader understanding of complex concepts.  Provides additional online features such as answers to in-book chapter review questions and self-assessment questions.  Presents information in a format and style that maximizes usefulness to students and teachers of medicine, allied health fields, and biology.  Contains numerous features designed to help students understand key immunologic concepts: high-quality illustrations, practical tables, chapter outlines, bolded key points, and focus questions in every chapter for self-assessment and review.  An eBook version is included with purchase. The eBook allows you to access all the text and figures, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Autoimmune diseases are conditions where the immune system attacks the body organs instead of foreign invaders. This book deals with the various mechanisms by which infectious agents can trigger autoimmunity such as molecular mimicry and polyclonal activation. An overview is given with regard to bacteria, viruses, and parasites associated with autoimmunity, and a summary is given on classical autoimmune diseases and the infecting agents that can induce them. Includes completely updated and new chapters Brings the reader up to date and allows easy access to individual topics in one place Identifies infectious agents as pathogenic or protective in many autoimmune diseases

COVID-19 Viral Sepsis: Impact on Disparities, Disability, and Health Outcomes introduces the concepts of viral sepsis, its origins, and its implications. COVID-19 is a leading cause of viral sepsis with considerable impact on morbidity and mortality. Early recognition of signs and symptoms of COVID-19 can potentially impact patient outcomes. The book opens with an overview of sepsis and viral sepsis. The discussion continues with an introduction to COVID-19 and related topics on its epidemiology, diagnosis, clinical manifestations, mild to moderate disease management, and the critical care treatment of COVID-19 patients. Sequelae of COVID-19, long-term consequences, challenges, current landscape, and future preparedness round out the coverage. COVID-19 Viral Sepsis: Impact on Disparities, Disability, and Health Outcomes is a valuable resource with contributions from experts on the front line of the COVID-19 crisis providing insight and key principles in the recognition, prevention, diagnosis, and treatment of sepsis due to COVID-19.

"From one of today's leading experts on the emerging science of the microbiome comes a ground-breaking book that offers, for the first time, evidence that the gut-microbiome plays a pivotal role in the health crises of the twenty-first century."--