Medicinsk mikrobiologi og virologi

Virus har sat dagsordenen i Jens Lundgrens arbejdsliv, lige siden han som helt ung læge stod ved sygesengen hos dødsmærkede aidspatienter og forskede i at finde en effektiv medicinsk mehandling til dem. Resultatet kan alverdens hiv-patienter takke ham for i dag.Siden coronapandemiens start har han knoklet for at hjælpe livstruede patienter og udvikle nye behandlinger med videnskabeligt dokumenteret effekt. Han har rådgivet de danske sundhedsmyndigheder og regeringen, og han har arbejdet tæt sammen med toppen af det amerikanske sundhedsvæsen under pandemigeneralen Anthony Fauci.I Vild virus giver han et unikt indblik i, hvad der sker bag kulisserne, når en virus truer os på livet og vender op og ned på vores hverdag. Bogen giver den første samlede beretning om de to vilde pandemiår: forskernes kapløb med tiden og en virus, der er en mester i at mutere, håndteringen af alle de udfordringer, virus pludselig kastede os ud i – og hvad vi har lært, så vi kan være bedre forberedte, når den næste virus udfordrer vores eksistens. For det vil ske: Pandemiernes tid er langtfra forbi.Bogen er blevet til i tæt samarbejde med Lars Igum Rasmussen, der som sundhedsredaktør på Politiken har dækket coronapandemien med mere end 200 nyhedsartikler, interviews, reportager og analyser.

A BBC RADIO 4 BOOK OF THE WEEKA TIMES SCIENCE BOOK OF THE YEARA SUNDAY TIMES SCIENCE BOOK OF THE YEAR'Powerfully argued... Fascinating and pacy' Sunday Times, Book of the Week'Superbly written... sure to please readers of Yuval Noah Harari or Rutger Bregman' The Times'Full of amazing facts' Observer'The book shines when it brings cutting-edge science to bear' Financial Times'A dizzying range of material' The Economist'A humbling story for humankind' SpectatorChallenges some of the greatest cliches about colonialism... A revelation' SATHNAM SANGHERA'Thrilling and eye-opening' LEWIS DARTNELL'Science and history at its best' MARK HONIGSBAUM'Unpicks everything we thought we knew... Mind blowing' CAL FLYNIn this revelatory book, Dr Jonathan Kennedy argues that germs have shaped humanity at every stage, from the first success of Homo sapiens over the equally intelligent Neanderthals to the fall of Rome and the rise of Islam.How did an Indonesian volcano help cause the Black Death, setting Europe on the road to capitalism? How could 168 men extract the largest ransom in history from an opposing army of eighty thousand? And why did the Industrial Revolution lead to the birth of the modern welfare state?The latest science reveals that infectious diseases are not just something that happens to us, but a fundamental part of who we are. Indeed, the only reason humans don't lay eggs is that a virus long ago inserted itself into our DNA, and there are as many bacteria in your body as there are human cells. We have been thinking about the survival of the fittest all wrong: evolution is not simply about human strength and intelligence, but about how we live and thrive in a world dominated by microbes.By exploring the startling intimacy of our relationship with infectious diseases, Kennedy shows how they have been responsible for some of the seismic revolutions of the past 50,000 years. Provocative and brimming with insight, Pathogenesis transforms our understanding of the human story, revealing how the crisis of a pandemic can offer vital opportunities for change.

Carbohydrate Nutrition covers the nutritional functionality of foods needed to address the metabolic disease epidemic. The source and structure of carbohydrates, including starch, human milk oligosaccharides, polyols, arabinoxylan, beta-glucan, and cellulose are introduced, as is their function in the small intestine and colon. Nutrition researchers, food scientists, food chemists, and those studying and researching related topics will benefit from this book and can apply their learnings to the design of foods with better carbohydrate nutrition.

Salmonella is a Gram-negative bacterium and a member of the Enterobacteriaceae family that causes infections in humans and animals, making it one of the most common causes of bacterial gastroenteritis worldwide. Since its discovery in the late 1800s, significant progress has been made in the understanding of its genetics, classification, pathogenesis, detection, prevention, control, and treatment. Numerous reviews and chapters on Salmonella have been published, but some gaps remain to be addressed. This book includes seven chapters that focus on the low-cost prevention, control, and treatment of salmonellosis in developing countries. It begins with a brief review of Salmonella, followed by chapters on the transmission of the organism in food and companion animals relevant to the One Health approach, CRISPR-Cas systems in Salmonella for pathogen typing in diagnosis and surveillance, the low-cost control of Salmonella using solar disinfection of water in resource-limiting communities, and transmission and antimicrobial resistance (AMR) in Salmonella across the One Health sector. This book also introduces a new concept of AMR reversal using traditional Chinese medicine. The information provided in this book will encourage Salmonella researchers, medical professionals, and students to further enhance their own research and education as well as encourage new researchers to include Salmonella in their future research initiatives.

A pacy, real-life page-turner by Reuters journalist on the global 100-days mission to identify and catch the next virus outbreak, codenamed DISEASE X, before it spreads worldwide.

Neglected Zoonoses and Antimicrobial Resistance: Impact on One Health and Sustainable Development Goals provides a thorough examination of how neglected zoonoses and antimicrobial resistance together hinder the achievement of sustainable development goals declared by the United Nations in the pursuit of a disease-free world. Neglected zoonotic diseases, as defined by the World Health Organization, are diseases likely to impact the livelihoods of livestock keepers and those living in periurban communities in developing countries. This book examines how such zoonoses affect the health of vulnerable farming populations and reduce the production capacity of their livestock. Written by internationally recognized experts in the field of livestock and poultry zoonoses, this book provides the reader with a comprehensive description of modern sustainable development goals and defines neglected zoonotic diseases and their impacts on human physical, mental, social, and economic health. Subsequent chapters systematically describe the epidemiology, hosts and transmission, disease process, economic significance, and prevention and treatment protocols of key neglected zoonotic diseases, including echinococcosis, leishmaniasis, zoonotic tuberculosis, anthrax, brucellosis, leptospirosis, borreliosis, rickettsioses, and rabies. The book concludes with an assessment of the obstacles to achieving Sustainable Development Goals and possible mitigation strategies for veterinary researchers and policymakers alike.

Diagnosis and Management of Poultry Coccidiosis provides a comprehensive overview of current trends in the control of Eimeria and coccidiosis. Chicken coccidiosis cost the global economy $12.58 billion in 2016, including lost productivity and expenditures associated with prevention and treatment. As a result, chicken producers have developed several management approaches to combat coccidiosis. With consumer and regulatory pressure, nutritional interventions, and the need to identify anticoccidial alternatives that do not impair growth performance, this book contemplates the antibiotic-free future of the chicken industry. Initial chapters in this book introduce readers to chicken coccidiosis and the identification and diagnosis of the Eimeria parasite. Subsequent chapters describe innate and adaptive immune responses of poultry to Eimeria and delve into the purification of Eimeria lifecycle stages and in vitro culture systems for the study of Eimeria. The latter half of the book examines a variety of modern immunization measures, dietary interventions, and anticoccidial medications designed to combat coccidiosis.

This second edition provides state-of-the-art and novel methods on antibiotic isolation and purification, identification of antimicrobial killing mechanisms, as well as methods for the analysis and detection of microbial responses and adaptation strategies. Antibiotics: Methods and Protocols,  Second Edition, guides readers through updated and entirely new chapters on production and design, mode of action, and response and resistance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Antibiotics: Methods and Protocols, Second Edition aims to inspire scientific work in the exciting field of antibiotic research.

This book, Gut microbiome and Brain Ageing, deals with the mechanisms and phenomenon that relates gut microbiome and aging of the brain. This book will bring forth the connection between good gut and brain aging and includes some cutting edge research topics dealing with gut physiology and its importance as future therapeutic option in neurological disorders. The gut microbiome's impact on neuronal function, mediated by neurotransmitters, vitamins, and neuroactive microbial metabolites, is an exciting area of investigation that this book thoroughly explores. It also covers the pivotal role of the gut microbiome in the etiology of various neurodegenerative disorders such as Alzheimer¿s disease (AD), Parkinson¿s disease (PD), depression, or multiple sclerosis (MS). It also explores the expanding understanding of the importance of the early-life gut microbiota and its implications for long-term health consequences. This book primarily addresses researchers, clinicians, and doctoral andgraduate students working in biomedicine, neurobiology, nutrition, microbiology, and translational medicine streams.

This textbook provides an up-to-date overview of the most important parasites in humans and their potential vectors. For each parasite, the book offers a concise summary including its distribution, epidemiology, life cycle, morphology, clinical manifestations, diagnosis, prophylaxis and therapeutic measures. Numerous tables, diagrams and over 200 colorful illustrations highlight the main aspects of parasitic infestations and present suitable control measures. 60 questions help to test readers' theoretical knowledge of the field. In short, the book is highly recommended for anyone looking to delve into the field of human parasitology. It is intended for students of biology and human medicine, medical doctors, pharmacists and laboratory staff alike. Furthermore, persons who plan to visit or live longer in endemic regions will find essential information on necessary preventive and control measurements.

"Comprehensive up-to-date guide to clinical and diagnostic virology. Individual chapters cover viruses from A-Z, which are then grouped under syndromes. Liberal use of tables and algorithms enable quick access to key information. An ideal introduction for interested trainees and a practical reference for more experienced hospital clinicians and GPs"--

'Will change your life' Chris Evans'Completely fascinating' Heston Blumenthal'Important and devastating' The TimesFrom a world-leading microbiome scientist and surgeon comes Dark Matter, a pioneering guide to hacking your microbiome for a healthier life.Our microbiome - the complex ecosystem of bacteria, viruses and other microbes inside us - is vital for our health and wellbeing. An invisible powerhouse whose potential we're only just beginning to understand, it influences our mood and appetite, determines how fast we run and even who we choose as a partner.In this ground-breaking book, microbiome expert Dr James Kinross takes us on a guided tour of our extraordinary inner universe and highlights the damage we inflict when we don't protect it. Showing through cutting-edge research and years of clinical experience, the practical steps we can all take to optimise the microbiome to live better, healthier lives.Now with a new, eye-opening afterword on the rise of home microbiome tests, IBS and FMTs. 'Addictive and illuminating' Dr Saliha Mahmood Ahmed, bestselling author of The Kitchen Prescription

Learn all the microbiology and basic immunology concepts you need to know for your courses and exams. Now fully revised and updated, Mims' clinically relevant, systems-based approach and abundant colour illustrations make this complex subject easy to understand and remember. Learn about infections in the context of major body systems and understand why these are environments in which microbes can establish themselves, flourish, and give rise to pathologic changes. This systems-based approach to microbiology employs integrated and case-based teaching that places the 'bug parade' into a clinical context. Effectively review for problem-based courses with the help of chapter introductions and 'Lessons in Microbiology' text boxes that highlight the clinical relevance of the material, offer easy access to key concepts, and provide valuable review tools. Approach microbiology by body system or by pathogen through the accompanying electronic 'Pathogen Parade' - a quickly searchable, cross-referenced glossary of viruses, bacteria and fungi A new electronic 'Vaccine Parade' offers quick-reference coverage of the most commonly used vaccines in current clinical practice Deepen your understanding of epidemiology and the important role it plays in providing evidence-based identification of key risk factors for disease and targets for preventative medicine. Grasp and retain vital concepts easily, with a user-friendly colour coded format, succinct text, key concept boxes, and dynamic illustrations. New and enhanced information reflects the growing importance of the human microbiota and latest molecular approaches Access the complete contents on the go via the accompanying interactive eBook, with a range of bonus materials to enhance learning and retention - includes self-assessment materials and clinical cases to check your understanding and aid exam preparation.

Intelligent Packaging: Current Technologies and Applications, Volume Six in the Developments in Food Quality and Safety series is the most up-to-date resource on topics such as Advances in the analysis of toxic compounds and control of food poisoning; Food fraud, traceability and authenticity; Revalorization of agrifood industry; Natural antimicrobial compounds and application to improve the preservation of food; Non-thermal processing technologies in the food industry; Nanotechnology in food production; and Intelligent packaging and sensors. This updated volume covers intelligent packaging by discussing the aspects of emerging technologies and strategies to obtain such packaging relevant to the development of traceable food products. Topics such as indicators, sensors, tracing devices, and intelligent packaging used in various food products, such as dairy, meat, fruits and vegetables are also explored. The series is edited by Dr. José Manuel Lorenzo and authored by a team of global experts in the fields of Food Quality and Safety, providing comprehensive knowledge to food industry personals and scientists.

A bacteriophage is a virus that can infect and replicate only inside a bacteria. They can kill bacteria without any negative effect on human or animal cells. They are referred to as phages and are the most common biological entities found on Earth. Bacteriophages vary in size, morphology, and genomic organization. Many phage-based technologies and therapies have been developed, especially in antibacterial treatments. There are several potential advantages of bacteriophages over antibiotics in terms of treating bacterial infections. Some of the benefits of bacteriophages are specificity of action (i.e., they kill only the pathogen they recognize), a considerable spectrum of activity, higher tolerability, and ease of administration. The results of various in-vitro studies have shown that bacteriophages could also be effective in the treatment of cystic fibrosis (CF) disorder. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the study of bacteriophages. It traces the recent developments in bacteriophage biology, technology and therapy. With state-of-the-art inputs by acclaimed experts of this field, this book targets medical students and professionals.