Kemi

Carbon nanomaterials have several applications, which is driving up scientific research into them. The book showcases the most recent advancements and research discoveries rather than just providing an overview. Each chapter offers authoritative insights into the ever-changing field of carbon-based nanomaterials, as written by top authorities in their respective domains. The book stands out for its persistent focus on real-world application. It is devoted to practical applications and is divided into four sections. The intriguing promise of carbon nanomaterials, their synthesis, and their possible uses set the stage for the adventure. Subsequently, the emphasis shifts to agriculture, where nanomaterials have been shown to improve plant health, fend against illnesses, promote growth and development, and even help detect and remove herbicides. The biomedical part explores the potential toxicological ramifications of these materials while introducing the reader to their ground-breaking role in drug delivery, tissue engineering, and the fight against fungal diseases. Overall, the book provides valuable insights and serves as a comprehensive resource for researchers and scientists across various interdisciplinary subjects.

This book outlines the unparalleled potential of NMR relaxation experiments to elucidate molecular dynamics for undergraduates to academics and those in industry.

This detailed volume presents a series of protocols dealing with different aspects of inclusion body (IB) processing, from cloning procedures to purification of refolded product. Commencing with chapters on upstream processing, looking into different expression strategies for IB production, the book continues with downstream applications, highlighting early protein purification and subsequent analytics, as well as success stories of IB-based processes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Inclusion Bodies: Methods and Protocols serves as an ideal resource for facilitating diverse aspects of IB processing.

This book explores recent progress in RNA secondary, tertiary structure prediction, and its application from an expansive point of view. Because of advancements in experimental protocols and devices, the integration of new types of data as well as new analysis techniques is necessary, and this volume discusses additional topics that are closely related to RNA structure prediction, such as the detection of structure-disrupting mutations, high-throughput structure analysis, and 3D structure design. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice that leads to quality research results. Authoritative and practical, RNA Structure Prediction serves as a valuable guide for both experimental and computational RNA researchers.

This reprint provides the most recent advancements and trends in the analysis of cultural heritage samples, including archaeological and bio-archaeological samples, confirming the growing public and academic interest in this field. The submitted papers cover different aspects of cultural and archaeological heritage protection, conservation, and restoration. The complexity of such samples, including archaeological samples, generally requires a multi-analytical approach. The integrated use of different analytical techniques, with the preference for noninvasive or micro-invasive ones, allows an in-depth understanding of the original materials and their degradation processes and helps obtain innovative solutions for the restoration and conservation of artworks.

Pollen is made up of many chemical constituents such as proteins, sugars, lipids, minerals and phytochemicals. These components make pollen products an excellent source of nutrients and antioxidants for consumers. However, mycotoxigenic fungi are also common in pollen, creating contamination from generated mycotoxins. With adequate monitoring, sampling, processing and storage of pollen the development of mycotoxins can be significantly prevented. Since pollen grain has strong membranes which can limit the bioavailability of some nutrients and phytochemicals, novel methods and pretreatments are required with special emphasis on microbiological pretreatment methodologies. Pollen Chemistry & Biotechnology summarizes current knowledge of the chemical composition of pollen, its importance as a functional food ingredient and its health promoting properties. As Introduction part a short elaborate about botanical characteristics and data, including morphology and anatomy of pollen and bee preferences, is given. Important factors such as the botanical and geographical origin, best practices for preservation of nutritional composition, bioactivity and safety of pollen are covered in full. The nutritional profile of pollen based on data for minerals, lipids and nutrients is presented. A detailed phytochemical profile of pollen based on data for phenolics, flavonoids, carotenoids, vitamins, bioactive compounds is also covered. Areas for the improvement of the bioavailability of different nutrients and bioactive compounds of pollen via applied pretreatments are presented, as are best practices for adequate pollen collection, procession and storage in order to obtain safe products. At the end, an overview about pollen bioactivity as reason to use it as source of pharmaceuticals is made.

Il volume tratta i seguenti argomenti: forza e campo elettrostatico, lavoro elettrico, potenziale elettrostatico, dipolo elettrico, legge Gauss, conduttori in equilibrio elettrostatico, condensatori ed energia del campo statico, condensatori e dielettrici, corrente elettrica, circuiti in corrente continua, campo e forza magnetica, forza di Lorentz e II legge di Laplace, sorgenti del campo magnetico, legge di Ampere, legge di Farady Neumann Lenz, equazioni di Maxwell.

Il volume tratta i seguenti argomenti: grandezze fisiche, cinematica, dinamica, lavoro ed energia, meccanica dei fluidi.

Il volume tratta i seguenti argomenti: ottiche geometriche e onde meccaniche con esercizi.

This book covers cadmium contamination of soil and plants, its sources, acute and long-term impacts on the environment and human health, and overall challenges posed by the global poisoning issue. Cadmium is among the elements that have been most broadly used by man over time, which has led to extensive pollution of surface soils, mainly associated with the mining and smelting of the metal and the addition of organic cadmium compounds to petrol. The release of cadmium into the atmosphere from various high-temperature processes has also led to surface contamination on a regional and even global scale. Cadmium is particularly firmly bound to humic matter in organic-rich soil and to iron oxides in mineral soil and is rather immobile in the soil unless present at very high concentrations. Plants grown on cadmium-rich soils incorporate cadmium, thus increasing the concentration of cadmium in crop plants. Cadmium thus enters the food chain through the consumption of plant material, whichposes important health risks to humans and animals. In this book, readers will find out about the latest mitigation strategies, including a multi-disciplinary approach to address cadmium contamination. Recent methods in cadmium detoxification, speciation, and molecular mechanisms are included, and the book offers the knowledge required for efficient risk assessment, prevention, and countermeasure. Divided into 3 parts, this book brings together expert contributions on cadmium toxicity. In the first part, readers will find out about the different sources and distribution of cadmium in soil and plant ecosystems. The second part of the book outlines the health risks linked to cadmium toxicity, and in the final part, readers will discover sustainable cadmium toxicity mitigation strategies and potential applications of recent biological technology in providing solutions. This book is a valuable resource for students, academics, researchers, and environmental professionalsdoing fieldwork on cadmium contamination throughout the world.

This book explores the topic of gyrolite and calcium silicate hydrates, focusing on their potential applications in wastewater purification and as additives in ordinary Portland cement. Divided into five chapters, the book provides a comprehensive description of calcium silicate hydrates and addresses challenges in reusing solid waste. It also covers the synthesis and application of gyrolite, offering technological recommendations for future studies. The results presented are supported by instrumental analysis techniques and thermodynamic calculations, allowing readers to delve into inorganic chemistry and materials characterization. The book is suitable for both researchers and students interested in chemistry and materials characterization, offering valuable insights and guidance in the field.

Energy storage and conversion technologies represent key research and industrial interests, given the proportionate growth of renewable energy sources. Extraordinary advancements in energy storage and conversion technologies are inextricably linked to the development of new materials. This Special Issue focuses on the most recent advances and findings in developing innovative energy storage and conversion technologies. It contains original research articles and reviews on the design, synthesis, characterization, energy storage mechanisms, and application of various materials for energy storage and conversion.

This Reprint is dedicated to the memory of Enrique Pedroso, Professor Emeritus of Organic Chemistry at University of Barcelona, who passed away at the age of 72 on September 2020. Professor Enrique Pedroso has been one of the pioneers of Nucleic Acids Chemistry in Spain, significantly contributing to the development of this highly interdisciplinary field which combines organic chemistry, biochemistry, pharmacology, materials chemistry, and biophysics. His major research achievements were accomplished in the synthesis of modified oligonucleotides and especially conjugates and cyclic oligonucleotides, as well as their analogues, which opened up new avenues in the search for novel applications of oligonucleotides.This Reprint comprises a collection of research or review articles prepared by international experts in Nucleic Acids, including nucleoside and oligonucleotide synthesis, nucleic acids structural studies, DNA repair, and biophysical characterization of DNA-targeting ligands, especially G-quadruplex binding drugs.

This volume ¿Cell Engineerring 11 - Biopharmaceutical Manufacturing: Progress, Trends and Challenges¿ is a source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation.The book comprises contributions of experts from academia and industry active in the field of cell culture development for the production of recombinant proteins, cell therapy and gene therapy, with consideration of Digital Twin¿s and facility design. The knowledge and expertise of the authors cover disciplines like cell biology, engineering, biotechnology and biomedical sciences. Inevitably, some omissions will occur in the test, but the authors have sought to avoid duplications by extensive cross-referencing to chapters in other volumes of this series and elsewhere. We hope the volume provides a useful compendium of techniques for scientists in industrial and research laboratories active in this field.

This book provides a comprehensive overview of Nuclear Magnetic Resonance (NMR) theory, its applications, and advanced techniques to improve the quality and speed of NMR data acquisition. In this book, the author expands his outstanding Ph.D. thesis and provides a valuable resource for researchers, professionals, and students in the field of NMR spectroscopy.The book covers quantum mechanics basics, and topics like density operators, pulse sequences, 1D pulse acquisition, INEPT (Insensitive nuclei enhancement by polarization transfer), product operators, and 2D NMR principles. It also explores innovative experiments like States HSQC (Heteronuclear Single Quantum Coherence) and echo-antiecho HSQC with gradients.In the subsequent chapters, the author discusses Pure Shift NMR, including PSYCHE (Pure Shift Yielded by Chirp Excitation) and its optimizations, such as waveform parameterization and time-reversal methods. The 'Discrete PSYCHE' approach and Ultrafast PSYCHE-iDOSY (Diffusion-ordered spectroscopy) are also highlighted.This book presents the POISE (Parameter Optimisation by Iterative Spectral Evaluation) software for real-time NMR experiment optimization, including pulse width calibration and Ernst angle optimization, and demonstrates applications across various NMR experiments.Lastly, the book examines accelerated 2D NMR data collection and the NOAH (NMR by Ordered Acquisition using 1H detection) supersequences, emphasizing automated pulse program creation using GENESIS (GENEration of Supersequences In Silico). Covered NMR experiments include 13C sensitivity-enhanced HSQC, 15N HMQC (Heteronuclear Multiple Quantum Coherence), dual HSQC, HSQC-TOCSY (Total Correlation Spectroscopy), HMBC (Heteronuclear Multiple Bond Correlation), and ADEQUATE (Adequate Sensitivity Double-Quantum Spectroscopy).

The Yearbook 2023 comprises all of the publications which appeared online at the internet portal www.brewingscience.de.All articles and papers are published in English, thus emphasizing the relevance of Germany as an international centre of research.Peer reviews by an international expert panel ensure the high scientifi c level of the articles.

Volatile Organic Compound Removal: Technologies and Functional Materials for VOC Removal details technologies and materials for the removal of volatile organic compounds (VOCs) from polluted air, covering not only the fundamental mechanisms, processes, and designs of the latest VOC abatement technologies, but also the characteristics and applications of advanced functional materials for VOC removal. The first half of this book centers on VOC abatement technologies including catalytic degradation, thermal oxidation, membrane separation, adsorption, absorption, and condensation, whereas the second half focuses on the applications of functional materials, especially novel nanomaterials, in VOC removal. Volatile Organic Compound Removal: Technologies and Functional Materials for VOC Removal is unique in covering both the fundamental mechanisms and practical applications of VOC abatement technologies, as well as focusing on the preparation, characterization, and application of novel functional materials for VOC removal.

Analysis of Microplastics and Nanoplastics comprehensively overviews the common analytical methods for microplastic and nanoplastic analysis. With a strong focus on sustainability, the book covers the analysis process from sampling, separation/enrichment, observation to identification of polymer composition and a presentation of data. This book presents the unique features of microplastics and nanoplastics as particle contaminants, their heterogenous distribution in the environments and biota, and the complexity and difficulty of their analysis compared with typical solvent contaminants. Analysis of Microplastics and Nonoplastics will provide researchers with a solid background to the environmental issues, analytical challenges, and current state-of-the-different available methods for micro and nanoplastics to start or develop research.

Deep Eutectic Solvents highlights well-established research and technology on applications of DESs in corrosion sciences, protein chemistry, and organic synthesis, as well as separation science. This book provides state-of-the-art research that will revolutionize modern practices. Neoteric solvents have been proposed as a better substitute to these harmful organic solvents, and scientists have come up with various neoteric solvents in the last few years like Deep Eutectic solvents (DESs). DESs are defined as a system formed from a eutectic mixture of Lewis or Brønsted acids and bases with various ionic species- whereas ionic liquids (ILs) consist of a discrete anion and a cation. DESs stand out as a greener and cheaper neoteric solvent as compared to ILs. DESs are denser than water and fairly polar, thus can be utilized as non-aqueous substitute to water in many separation processes. DESs have very high distribution coefficient of solutes, and even dissolves gases and metal oxides selectively. They also readily dissolve organic macromolecules, thereby becoming useful in pharmacological applications.

Specification of Drug Substances and Products: Development and Validation of Analytical Methods, Third Edition contains chapters discussing the unique requirements for the universal critical quality attributes, as well as the specific tests required to characterize and control different types of products, ranging in complexity from small molecules in immediate release oral dosage forms to complex products such as drug-antibody conjugates and mRNA-based products. This substantially expanded revision of the second edition will serve as practical comprehensive reference for scientists, managers, educators, and consultants involved in the development and regulation of pharmaceutical products.

Pharmaceutical chemistry (PC) represents a dynamic field of research that plays a pivotal role in the development of life-saving pharmaceuticals. PC is a precise science: One needs to rely on the accuracy of previous discoveries that have provided massive amount of precious information and databases as a solid foundation to move forward. PC is also an art where the artist uses a subtle mixture of knowledge, experimental learning, creativity, intuition, boldness, and serendipity to paint the right canvas. Nature often serves as a stimulus for pharmaceutical chemists. Many drugs are derived from natural compounds found in plants, fungi, or microorganisms. Chemists study these natural sources, seeking inspiration to design synthetic molecules that mimic the therapeutic properties of the originals while optimizing their characteristics. Francis Collins, geneticist and expert in the pharmaceutical industry, explains that the molecular cause of 4,000 diseases is no longer a secret to humanity, but there are only treatments available for 250 of them. Therefore, the world requires more professionals who can produce better medicines and solve more needs. For this reason, it is urgent to discover a new system, new drugs, better industrial processes and faster responses for rare and complex diseases. That is the importance and need for more students in love with PC. It is the author's wish that volumes 1 and 2 of this series may serve as motivation for students who intend to get started in the exciting world of drug design, synthesis and development. There is no nobler objective than improving health and quality of life of the human race. The unprecedented increase in human life expectancy, which has almost doubled in a hundred years, is mainly due to drugs and to those who discovered them. It is more important to create awareness in the student that he/she is responsible for his own learning and not simply a passive consumer of information. In this way we will be able to train versatile professionals with an attitude of transformative social change. Drug Design and Action is trated in a separate volume ISBN 978-3-11-131654-3.

In this book recent developments in dehydrogenation reactions catalyzed by 3d-metals are discussed. With continue efforts to develop sustainable chemical production the discovery of new catalysts and catalytic procedures for (de)hydrogenation reactions are a subject of great interest to the chemistry community. Additionally, (de)hydrogenation reactions enable the creation of closed-loop production cycles that support a circular economy. The chapters presented include the synthesis of heterocycles and tandem-multicomponent (three or more) reactions through dehydrogenative strategy, as well as the conversion of ethanol to n-butanol, higher oxidized hydrocarbons like acids, ester, amides from alcohols, ¿-alkylation of amines, ketones, and amides with alcohols and mechanistic understanding of dehydrogenation reactions with high-valent metals. With contributions from experts in the field, the book is a valuable resource for scholars working in the field of organometallic chemistry,catalysis, medicinal chemistry, as well as researchers in the industry.

This Special Issue includes ten papers by 45 authors, including excellent cutting-edge research from Japan. Looking at the papers reported here, Japan's liquid crystalline research is a global pioneer within this field. It is clear that Japanese liquid crystalline research will further develop in the future.

Non-ferrous metals and alloys are essential resources for the development of modern industries. With the depletion of natural minerals, non-ferrous metal recovery from metallurgical residues attracts researchers from multidisciplinary areas. Ideas for new recovery routes reduce pressure on natural resources and the environment, thus benefiting better manufacturing sustainability. This Special Issue primarily considers papers focused on the theoretical and engineering aspects of processing metal recovery from metallurgical residues.