Magnetisk resonans

This book consists of a series of lectures introducing what the author believes to be the theoretical minimum for the understanding of nuclear spin dynamics, the branch of physics underpinning magnetic resonance techniques such as NMR and MRI.

This second edition is primarily dedicated to MR-Enterography, an imaging modality whose reliability for intestinal assessment in patients suffering from inflammatory bowel diseases has gained increasing consensus.The performance of this technique has been significantly enlarged over the last years, due to its undoubted advantages in terms of exhaustive evaluation of the abdominal cavity and safeness due to the lack of radiation exposure. The first part is focused on MR-Enterography standard protocol. Nevertheless, additional sequences, technical novelties and common pitfalls are reported and discussed.  In the second section, the typical intestinal and extra-intestinal findings related to Crohn's disease are described in detail. In this edition, more emphasis has been put on practical topics, useful in the daily clinical practice: anatomical changes after surgical procedures, structured reporting and emerging clinical applications over inflammatory bowel diseases.Another part is dedicated to Magnetic Resonance Imaging of the anal canal, including technical aspects and clinical implications.The text is largely complemented by diagnostic images. Nonetheless, at the end of the book 30 illustrated cases show different clinical scenarios evaluated with MR-Enterography and Magnetic Resonance Imaging of the anal canal.

This book discusses the present and the future perspectives of NMR techniques for environmental evaluations.

Exploring the newest developments in residual dipolar coupling measurement and analysis through authoritative accounts, this book provides a comprehensive overview on the fundamentals, analysis and applications.

This textbook describes the theory underlying each instrumental procedure and applications of all instrumental methods. It comprehensively covers the instrumental methods of chemical analysis, chromatography, thermal methods of chemical analysis, electrochemical methods, and instrumental methods of analysis of inorganic compounds. These include thermogravimetric analysis, differential thermal analysis, thermometric titrations, and some miscellaneous thermal methods like derivative thermogravimetric analysis, thermobarography, differential scanning calorimetry, thermomechanical analysis, and electric thermal analysis, flame photometry, fluorimetry and phosphorimetry, nephelometric and turbidimetric techniques, refractory and interferometry, and X-ray methods. Each chapter consists a set of problems to aid self-learning. This textbook is highly useful for graduate and postgraduate students on chemistry and its allied fields. It can also be used as a quick reference material by professionals working in the various fields of chemistry and material science.

This book provides an overview of the contemporary integrated biology approaches for solving structures and understanding mechanisms of complex biological systems.

Written by active investigators in the field, this book describes state-of-the-art methods that can accelerate the acquisition of 2D NMR spectra in solution-state NMR.

This book details the latest research and development in the use of magnetic resonance imaging and spectroscopy as tools to give quantitative insights concerning late stage pharmaceutical formulation, tablet manufacturing and drug dissolution behaviour. The book combines different facets of magnetic resonance and highlights the use of spatial resolution (MRI) and how this adds to the knowledge base to further our understanding of the microscopic physicochemical processes occurring during drug release from solid dosage forms. New topics, that have not been thoroughly reviewed elsewhere, are covered including the applications of solution state magnetic resonance in process scale up, reaction monitoring/understanding and process analytical technologies (PAT); dissolution testing; and counterfeit analysis. Solid state NMR and its role in understanding phase separation in dispersions, polymorphism and crystallography is included and magnetic resonance imaging and its use in assessing tablet dissolution performance, mass transport and mixing in hot melt extrusion (HME) are covered.Focusing on late stage development rather than molecular drug discovery provides a unique approach and the book will appeal to a diversity of disciplines using spectroscopy for study. Aimed at researchers in drug development, manufacture and formulation in both industry (pharmaceutical companies) and academia (pharmacy program), it includes examples, where appropriate, of studies on commercially available pharmaceutical products.

This textbook is designed for graduate students to introduce the basic concepts of Nuclear Magnetic Resonance spectroscopy (NMR), spectral analysis and modern developments such as multidimensional NMR, in reasonable detail and rigor. The book is self-contained, so, a unique textbook in that sense with end of chapter exercises included supported by a solution manual. Some of the advanced topics are included as Appendices for quick reference. Students of chemistry who have some exposure to mathematics and physics will benefit from this book and it will prepare them to pursue research in different branches of Chemistry or Biophysics or Structural Biology.¿