Playing With Devil- Covid 19 Related Encephalitis Lethargica Pandemic - Ravikumar Kurup - Bog

The oxidative stress& osmotic stress of global warming can induce aldose reductase mediated conversion of glucose to fructose via the enzyme sorbitol dehydrogenase. This also leads to induction of fructokinase, generation of fructose, fructosemia and fructositis. The increased fructose can fructosylate proteins producing antigenic proteins and autoimmune disease. Thus fructosemia can contribute to neurodegeneration, psychiatric disorders like schizophrenia, bipolar mood disorder, autism, ADHD, la tourette¿s &encephalitis lethargica. Fructose can produce ATP depletion and oxidative stress. Oxidative stress can induce NFKB producing chronic inflammation &TNF alpha can produce insulin resistance acting at the level of insulin receptor. The insulin resistance activates the aldose reductase fructokinase system still further which is also further activated by the osmotic and oxidative stress of extremes of climate like global warming. This produces syndrome with anti-glycolytic enzyme anti-basal ganglia antibodies. Neanderthals are impulsive and creatures of emotion dominated by the brain stem structures and cerebellum. Impulsive magical societies can be compared to societies of devil.