Systems Medicine and Network-Based Pharmacology - Lida Murdock - Bog

Systems medicine refers to the study of the human body by incorporating environmental, physiological and biochemical interactions. It evaluates disease by the integration of large volumes of patient datasets, while offering the scope for personalizing healthcare strategies by developing a novel classification of disease. The redefinition of disease is done on the basis of mechanisms in place of analyzing the symptoms, which provide therapeutic targets, involving network pharmacology and drug repurposing. Network pharmacology is an interdisciplinary science based on pharmacology, network biology, systems biology, bioinformatics, computational science, and other related scientific disciplines. The usage of network-based insight allows network pharmacology to systematically reflect and uncover the biological foundation of complex diseases and medication. It uses a systems approach to generate significant insights for drug development and has the capability to serve as a foundation for developing drugs for complicated diseases. This book discusses the fundamentals as well as modern approaches of systems medicine and network-based pharmacology. Those in search of information to further their knowledge will be greatly assisted by it.