Bioteknologi

This book provides an excellent platform for understanding the chemical processes involved in food transformation. Starting with the examination of major food components, such as water, carbohydrates, lipids, proteins and minerals, the author further introduces the biochemistry of digestion and energy metabolism of food ingredients. The last section of the book is devoted to modern food technologies and their future perspectives.

'Will change your life' Chris Evans'Completely fascinating' Heston Blumenthal'Important and devastating' The TimesFrom a world-leading microbiome scientist and surgeon comes Dark Matter, a pioneering guide to hacking your microbiome for a healthier life.Our microbiome - the complex ecosystem of bacteria, viruses and other microbes inside us - is vital for our health and wellbeing. An invisible powerhouse whose potential we're only just beginning to understand, it influences our mood and appetite, determines how fast we run and even who we choose as a partner.In this ground-breaking book, microbiome expert Dr James Kinross takes us on a guided tour of our extraordinary inner universe and highlights the damage we inflict when we don't protect it. Showing through cutting-edge research and years of clinical experience, the practical steps we can all take to optimise the microbiome to live better, healthier lives.Now with a new, eye-opening afterword on the rise of home microbiome tests, IBS and FMTs. 'Addictive and illuminating' Dr Saliha Mahmood Ahmed, bestselling author of The Kitchen Prescription

This book looks at chemmotological solutions to important questions surrounding sustainability and environmental safety of transport - both key priorities within the global strategy of sustainable development. Bringing together expanded versions of selected papers presented at the 8th International Scientific-Technical Conference: Problems of Chemmotology - Theory and Practice of Rational Use of Conventional and Alternative Fuels and Lubricants, contributors present solutions to problematic questions, including choosing feedstock and technologies of its processing for manufacturing alternative fuels, development and implementation of measures for improving environmental safety of transport, minimizing exhaust gases emission from transport, introducing new solution or improvements in systems of fuels supply and infrastructure, and changes in legislative and regulatory base for fuels and lubricants use. This collection will be an invaluable reference for researchers, professionals, and students involved in alternative aviation fuels, transport engineering, sustainable transport development, and fuels and lubricants.

This book surveys the distinctions that underlie the unbound potential and existential risks of life expansion and radical modifications posed by a transhuman world. Humanness is in flux as human bodies are being hacked and altered in their quest for super wellness, super intelligence and super longevity. Now is the time to discuss how best to think about dealing with bodies that have been hacked to exceed natural physical limits or more technically, species typical functioning. Enter the advent of transhumanism to take uncertainty by the horns. According to transhumanists, death is unnecessary and medical conventions undermine the possibility to radically evolve. To biohackers, there is no need to wait to explore the risks that conventional medicine dares not. This book is of interest to anyone interested in tapping into this growing movement of modifying the human body as it is right now.

This book describes for first time the synthesis and intensified process design in the production of top biofuels. The production of biofuels is not new. In 2019, global biofuel production levels reached 1,841 thousand barrels of oil equivalent per day, in stark comparison to the 187 thousand barrels of oil equivalent per day that was produced in 2000. Growth has largely been driven by policies that encourage the use and production of biofuels due to the perception that it could provide energy security and reduce greenhouse gas emissions in relevant sectors. From a technical point of view, almost all fuels from fossil resources could be substituted by their bio-based counterparts. However, the cost of bio-based production in many cases exceeds the cost of petrochemical production. Also, biofuels must be proven to perform at least as good as the petrochemical equivalent they are substituting and to have a lower environmental impact. The low price of crude oil acted as a barrier to biofuels production and producers focussed on the specific attributes of biofuels such as their complex structure to justify production costs. Also, the consumer demand for environmentally friendly products, population growth and limited supplies of non-renewable resources has now opened new windows of opportunity for biofuels. The industry is increasingly viewing chemical production from renewable resources as an attractive area for investment. This book uniquely introduces the application of new process intensification techniques that will allow the generation of clean, efficient and economical processes for biofuels in a competitive way in the market.

This book covers all aspects of hybrid breeding technologies applied for crop improvement in major field crops. The different male sterility systems such as genetic male sterility (GMS), cytoplasmic male sterility (CMS), cytoplasmic and genetic male sterility (CGMS), and male sterility induced by the photoperiod (PGMS), temperature (TGMS), and chemicals are discussed in detail. The different chapters in this book provide a timeline of the key breakthroughs witnessed in the field of plant male sterility technologies, their application in hybrid breeding, and the relevance to the current need for food security. In-depth insights into the genetic and regulatory mechanisms of plant male sterility have been presented. This includes discussion on a variety of molecular players that induce male sterility and rescue male fertility in the hybrid plants. To enhance this book's appeal, more emphasis has been given on the modern emerging approaches such as construction of heterotic pools that could boost hybrid breeding for enhanced crop performance amid climate change and growing population worldwide.  This book is a guide for growers and industries related to field and horticultural crops. Further, it is a useful reference for plant breeders, researchers and extension workers, and students. The material can also be used for teaching undergraduate and postgraduate courses.

Quantum dots (QDs) are important in the research and industrial fields due to their diverse properties and technological importance. Recently, QDs have been found to be suitable for biological, biomedical, agricultural, and food science applications. Many research articles, review papers, and internet sources have published on the use of QDs to improve plant growth and yield, but a comprehensive overview in book form has not been available to date. This book provides detailed information on synthesis, functionalization, and the use of various types of quantum dots for plant systems. It also addresses the current state of knowledge on sensing mechanisms of QD-based biosensors used for microorganisms, including bacteria, fungi, and plant virus detection. This book also offers in-depth knowledge related to QDs used for plant growth, nutrients, and plant protection from micro-organisms. This volume is beneficial as one comprehensive resource for students, researchers, scientists, technicians, academicians, and industrialists.

This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in fruit crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing in many of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The seven chapters each dedicated to a fruit crop and a fruit crop group in this volume elucidate different types of abiotic stresses and their effects on and interaction with the crops; enumerate the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. 

This book explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues.  It covers the design concept of peptide therapeutics from fundamental principles using structural biology and computational approaches. The chapters are arranged in a linear fashion. A fresh graduate or a scientist who works on small molecules can use this to follow the design and development of peptide therapeutics to use as understanding the basic concepts. Each chapter is written by experts from academia as well as industry. Rather than covering extensive literature, the book provides concepts of design, synthesis, delivery, as well as regulatory affairs and manufacturing of peptides in a systematic way with examples in each case. The book can be used as a reference for a pharmaceutical or biomedical scientist or graduate student who wants to pursue their career in peptide therapeutics. Some chapters will be written as a combination of basic principles and protocol so that scientists can adopt these methods to their research work. The examples provided can be used to perform peptide formulation considerations for the designed peptides. The book has nine chapters, and each chapter can be read as an independent unit on a particular concept.

This interdisciplinary book covers the fundamentals of optical whispering gallery mode (WGM) microcavities, light¿matter interaction, and biomolecular structure with a focus on applications in biosensing. Novel biosensors based on the hybridization of WGM microcavities and localized surface plasmon resonances (LSPRs) in metal nanoparticles have emerged as the most sensitive microsystem biodetection technology that boasts single molecule detection capability without the need for amplification and labeling of the analyte. The book provides an ample survey of the physical mechanisms of WGMs and LSPRs for detecting affinity, concentration, size, shape and orientation of biomarkers, while informing the reader about different classes of biomolecules, their optical properties and their importance in label-free clinical diagnostics.This expanded and updated second edition features a new chapter that introduces the reader to advanced in vivo biosensing techniques using WGM microcavities, looking at photothermal sensing, methods for trapping neutral atoms around WGM microcavities, and practical aspects of optoplasmonic sensing. The second Edition now provides a comprehensive introduction to the use of WGM microcavities in physical sensing which includes measurements with frequency combs, macro and micro (one atom) lasers, gyroscopes, optomechanical and parity-time-symmetric sensor devices.Chapter-end problems round out this comprehensive and fundamental textbook, inspiring a host of up-and-coming physicists, bioengineers, and medical professionals to make their own breakthroughs in this blossoming new field. This textbook can be used for both introductory and advanced courses about the modern optics of optical microcavities.

This book on 3D printing in oral health science aims to equip the reader with a sound understanding of contemporary clinical applications in all fields of dentistry and their future directions. In the last few years, the development of 3D printing for medical and dental applications has increased tremendously. Advancements in 3D printing create the possibility of customized products, savings on small-scale productions, ease of sharing and processing of patient image data, and educational up-gradation. Looking at the dental specialties, it is evident that 3D printing has applications in all aspects of oral health science including prosthodontics, oral surgery, periodontics, endodontics, and orthodontics. This book will cover all major fields in dentistry and will help the practitioner in the process of decision-making and apply concepts in clinical or laboratory practice. It is based on current scientific evidence to provide readers with an up-to-date contemporary understanding of the subject, both from the clinical and the technological side. The book is a valuable asset for all who specialize in 3D printing and for those interested in learning more about this field.

This book provides cutting-edge, up-to-date research findings on the use of bionanocomposites in biodegradable and environmental applications, while also detailing how to achieve bionanocomposites preparation, characteristics, and significant enhancements in physical, chemical, mechanical, thermal properties and applications. This book on biodegradable and environmental properties of bionanocomposites provides a comprehensive and updated review of major innovations in the field of polymer-based bionanocomposites for biodegradable and environmental applications. It covers properties and applications, including the synthesis of polymer-based bionanocomposites from different sources biomaterials-based composites and tactics on the efficacy and major challenges associated with successful scale-up fabrication on bionanocomposites.It is an essential reference for future research in bionanocomposites as topics such as sustainable, biodegradable, and environmental methods for highly innovative and applied materials are current topics of importance. The book covers a wide range of research on bionanocomposite and their biodegradable and environmental applications. Updates on the most relevant polymer-based bionanocomposite and their prodigious potential in the fields of biodegradable and the environment are presented. Leading researchers from industry, academy, government, and private research institutions across the globe contribute to this book. Scientists, engineers, and students with interest in the most important advancements in the field of bionanocomposites involving high-performance bionanocomposites will benefit from this book which is highly application-oriented.   

Over the last half century, a quiet revolution has taken place. In a series of breathtaking discoveries, biochemist Thomas Cech and a diverse cast of brilliant scientists have revealed RNA at the centre of biology's greatest mysteries, from how life began to what makes us human to why we age. At last, The Catalyst pulls back the curtain to show how RNA-long sidelined as the passive servant of DNA-defines life from its very origins to our future in the twenty-first century. Recounting his own paradigm-shifting discovery that RNA can catalyse biochemical reactions, as well as his work on the "fountain of youth" telomerase, Cech unfolds how RNA holds the key to the intricate machinery of our cells, the critical processes of ageing and disease and the spectacular powers of breakthrough therapies from CRISPR to mRNA vaccines. From one of our foremost scientists, The Catalyst is a must-read guide to the present and future of biology and medicine.

CMOS technologies and their ongoing downscaling trend have opened an avenue to developing integrated systems for life sciences. This book explores the theoretical and practical aspects of CMOS biosensors and discusses the fundamentals of biological applications and microfabrication.

This book provides an authoritative overview of emerging pollutants in sewage sludge and soils. It traces the latest research and new trends on the characterization, removal and treatment of such pollutants in urban and industrial sewage sludge and soils. The book covers topics such as antibiotic resistance, fate and environmental impact of contaminants of emerging concern, environmental transmission of human pathogenic viruses and their effect on soil, and the repercussion of various emerging pollutants on biodiversity. It also offers a case study of the epidemiology-based surveillance of SARS-CoV-2 in wastewater and sludge.The book appeals not only to researchers and professionals working with emerging contaminants, but also to policy makers and a broader audience interested in learning more about the effects of these contaminants in human and environmental health.

This is a graduate-level introduction to quantitative concepts and methods in the science of living systems. It relies on a systems approach for understanding the physical principles operating in biology. Physical phenomena are treated at the appropriate spatio-temporal scale and phenomenological equations are used in order to reflect the system of interest. Biological details enter to the degree necessary for understanding specific processes, but in many cases the approach is not reductionist. This is in line with the approach taken by physics to many other complex systems.The book bridges the gap between graduate students¿ general physics courses and research papers published in professional journals. It gives students the foundations needed for independent research in biological physics and for working in collaborations aimed at quantitative biology and biomedical research. Also included are modern mathematical and theoretical physics methods, giving the student a broad knowledge of tools that can shed light on the sophisticated mechanisms brought forth by evolution in biological systems. The content covers many aspects that have been the focus of active research over the past twenty years, reflecting the authors' experience as leading researchers and teachers in this field.

This book reviews the advances in data gathering and processing in the biotech laboratory environment, and it sheds new lights on the various aspects that are necessary for the implementation of intelligent laboratory architecture and infrastructure. Smart technologies are increasingly dominating our everyday lives and have become an indispensable part of the industrial environment. The laboratory environment, which has long been rather conservative, has also set out to adapt smart technologies with regards to Industry 4.0 and the Internet of Things (IoT) for the laboratory. Due to the heterogeneity of the existing infrastructure and the often complex work processes, standardization is slow, e.g. to implement device interfaces or standardized driver protocols, which are urgently needed to generate standardized data streams that would be immanent for post-processing of data.Divided into 9 chapters, this book offers an authoritative overview of the diverse aspects in the generation and recording of uniform data sets in the laboratory, and in the processing of the data and enabling seamless processing towards machine learning and artificial intelligence. In the first part of the book, readers will find more about high throughout systems, automation, robotics, and the evolution of technology in the laboratory. The second part of the book is devoted to standardization in lab automation, in which readers will learn more about some regulatory aspects, the SiLA2 standards, the OPC LADS (Laboratory and Analytical Device Standard), and FAIR Data infrastructure

This edited volume emphasizes how microorganisms have become a reliable pillar of biotechnology. The authors discuss advances in synthetic biology and genetic engineering that have made it possible to reprogram the microbial cellular capabilities. This enables an economically viable production of high-value products at an industrial level.The first part of the book provides an overview of synthetic biology and genome editing tools for engineering microbial cell factories in modern fermentation. Readers also learn how high-throughput bioprocessing methods are used to recover and purify microbial products.The remaining parts of this book explore the implementation and challenges of these upstream and downstream processing techniques for manufacturing high-value products. Cost-effectiveness and quality-control are key factors, when discussing the production of low-molecular-weight products, biopharmaceuticals, biopolymers and protein-based nanoparticles.This book is a valuable resource for biotechnologists both in the industry and in academia.

This book focuses on understanding biomimetic architecture and its role as a sustainable design tool. It presents the role of biomimicry in mitigation and adaptation to climate change and examines how biomimetic architecture can provide healthy solutions to limit the spread of COVID-19 in buildings and cities. Coverage includes global examples of biomimetic approaches and buildings, an evaluation of the performance of biomimicry applications in architecture to illustrate best practices, and an exploration of how nature can offer inspiration in building design to conserve resources and save energy use as well as curb carbon emissions - a reaffirmed goal of COP 26 and an outcome of Glasgow Climate Pact. Finally, the book presents guidelines to enhance urban areas and healthier spaces in buildings to meet COVID-19 social distance regulations and beyond.Examines global applications of biomimicry in architecture;Highlights the importance of biomimicry in driving livability in cities and buildings;Explores the role of biomimetic architecture in mitigating climate change."e;The line of argument developed is highly relevant to the present, in addition to being original and pertinent to research on urban regeneration, especially in regard to the exploration of the use of biomimicry architecture in response to changing urban demands."e; -Alessandra Battisti, Ph.D., Professor of Architecture, University of Rome La Sapienza-

This book offers a comprehensive description and analysis of natural hazard warnings, drawing on perspectives from the social sciences, physical sciences, and interdisciplinary fields such as disaster studies to articulate a distinction between traditional warnings and what might be called interdisciplinary warnings. Traditional warnings approach warning technology, design, and application from a principally scientific and technical perspective. Human factors, while considered, often are of secondary concern. Interdisciplinary warnings, on the other hand, maintain a critical emphasis on the technical merits of warning systems, but also ask, "e;Will psychological and community factors such as culture and structure shape how the system is used, and, if so, can this information be incorporated into system design preemptively to make it more effective?"e; Given the absence of systematic work on interdisciplinary warnings, a book-length monograph discussing and synthesizing knowledge from the various fields focused on warnings and warning response is of critical importance to both academics and practitioners. Broadly conceived, the book presents readers with an in-depth overview of warnings, interdisciplinary research, and interdisciplinary collaboration. The book holds appeal for a very broad audience: scholars; practitioners; and academic, vocational, and technical instructors both in University and non-University settings. It is of interest to academic scholars due to the interdisciplinary treatment of warnings as well as the general presentation of up-to-date scholarship on warning theory. Additionally, scholars interested in interdisciplinary work in general and those focusing on disaster warnings find within the volume a framework for developing collaborative research partnerships with those from other disciplines. As well, the book offers practitioners --emergency managers, mitigation specialists, planners, etc. --a more comprehensive perspective on emergency response in practice, allowing for better development and application of warning policy. Finally, the book appeals to instructors both inside and outside the academy. The authors envision the book useful to professors teaching both graduate and undergraduate-level courses in Sociology of Disaster, Emergency Management Planning, Homeland Security, Disaster Response, Disaster Mitigation, and Business Continuity and Crisis Management. A robust market also exists among professional organizations, perhaps most notably FEMA, which offers countless online and in-person training courses via the National Training Program, Emergency Management Institute (EMI), and other venues.

Computational and Network Modeling of Neuroimaging Data provides an authoritative and comprehensive overview of the many diverse modeling approaches that have been fruitfully applied to neuroimaging data. As neuroimaging is witnessing a massive increase in the quality and quantity of data being acquired, this book gives an accessible foundation to the field of computational neuroimaging, suitable for graduate students, academic researchers, and industry practitioners who are interested in adopting or applying model-based approaches in neuroimaging. It is widely recognized that effective interpretation and extraction of information from complex data requires quantitative modeling. However, modeling the brain comes in many diverse forms, with different research communities tackling different brain systems, different spatial and temporal scales, and different aspects of brain structure and function. This book takes a critical step towards synthesizing and integrating across different modeling approaches.

Bioactive Materials for Soft Tissue Regeneration covers human tissue and its classification as hard tissue such as bone and soft tissue like skin, muscle, tendon, blood vessel, nerve etc., and including organs such as heart, liver, lung. Regenerative medicine deals with both hard tissue and soft tissue regeneration and is one of the most important part of the modern medicine with significant clinical needs including general surgery, plastic surgery, burn and wound healing, cardiovascular disease treatments. Based on the authors' previous research and review of the international advances in hard tissue regeneration, this book focuses on the hard tissue regeneration using bioactive materials. Sections cover biomaterials for entire human tissue regeneration, which is key important for research and development in the field of biomedical engineering and the medical device industry. Readers will find this to be a comprehensive review of the most updated advances of the research in bioactive materials for soft tissue repair and regeneration, along with perspectives for future directions of research and development in this field.

This edited book focuses on the role and use of VR for healthcare professions in both health and rehabilitation settings. It is also offers future trends of other emerging technology within medicine and allied health professions. This text draws on expertise of leading medical practitioners and researchers who utilise such VR technologies in their practices to enhance patient/service user outcomes. Research and practical evidence is presented with a strong applied emphasis to further enhance the use VR technologies within the community, the hospital and in education environment(s). The book may also be used to influence policymakers on how healthcare delivery is offered.

This book highlights the importance of waste to health in which waste is safely converted to value-added products via bioprocess technologies. Providing fundamental concepts and applications, it also offers readers the methodology behind the operation of a variety of biological processes used in developing valuable products from waste.

The fourth edition of Process Validation in Manufacturing of Biopharmaceuticals is a practical and comprehensive resource illustrating the different approaches for successful validation of biopharmaceutical processes.