Sygdomme og lidelser

Dieses Buch bietet Sicherheit: Effiziente Diagnostik, verwertbare Ergebnisse, zuverlässige Bewertung. Fehlinterpretationen können zu aufwändiger Zusatzdiagnostik und Therapie führen und belasten unnötig den Patienten.Für alle, die endokrinologische Funktionstests durchführen und bewerten: Endokrinologen, Diabetologen, Gynäkologen, Urologen, Andrologen, Pädiater, Internisten ¿Alles, was wichtig istDie 200 wichtigsten Funktionstests und HormonparameterRadiologisches/nuklearmedizinisches Basiswissen für die DiagnostikGenotyp-Phänotyp-Beziehung für genetisch bedingte EndokrinopathienValidierte Scoring- und Grading-Systeme für die EndokrinologieAusführliche Tabellen zu Normbereichen und verlässlichen Cut-off-Werten unter besonderer Berücksichtigung von Geschlecht, Alter, BMI, Pubertätsphasen, Zyklusphasen, akuten Erkrankungen, Medikamenten ¿Detailiert und praxisrelevantIndikationen, Kontraindikationen, NebenwirkungenTestvorbereitung, RahmenbedingungenKonkrete Handlungsanleitungen zur TestdurchführungSichere Bewertung der ErgebnissePraxistipps und potentielle FallstrickeNEU u.a24-h-Blutdruckmessung, Analyse der PulswellengeschwindigkeitDurchführung und Auswertung der SchilddrüsenpunktionOsteodensitometrie mit BefundungsbeispielenScoring/Grading-Systeme in der Endokrinologie incl. Fibrose ScoresTestverfahren für periphere und autonome Neuropathie-DiagnostikOrientierend an Empfehlungen nationaler und internationaler Fachgesellschaften

Integrative Oncology (IO) is an evolving evidence-informed field of medicine with little high-quality professional literature currently available to support clinical practice. This book provides a robust introduction to integrative oncology and a practical toolkit for clinicians working with breast cancer patients. Breast cancer is the commonest cancer in women globally with growing incidence, and breast cancer patients are the most frequent users of integrative oncology practices. This book addresses the whole person journey from prevention, to diagnosis, treatment and survivorship. The approaches and tools discussed can help guide clinicians on how to support better quality of life, improve patient resilience, minimise the side effects of treatment and optimise clinical outcomes for people impacted by breast cancer. Healthcare professionals are asking for further education on Integrative Oncology, as evidenced by the BSIO (British Society for Integrative Oncology) survey results, webinars and conference engagements. Our growing BSIO membership highlights the need to educate and train healthcare professionals, and this book is written by clinicians for clinicians.

This detailed volume explores the dynamic landscape of patient-derived xenograft (PDX) generation and applications. After a few chapters examining the evolution of PDXs, tracing their roots and contextualizing their significance in the broader narrative of cancer research, the book continues with methodologies for generating PDXs from diverse clinical tissue samples as well as for utilizing PDXs in various specific cancer types. From the development of humanized PDX models to the exploration of protein expression through advanced techniques including multiplex immunohistochemistry, Western blotting, and immunoprecipitation, the chapters offer a comprehensive toolkit for researchers and clinicians alike. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Patient-Derived Xenografts: Methods and Protocols serves as an ideal interdisciplinary guide for understanding the intricate processes that underscore translational cancer research.

"Anthony Fauci is arguably the most famous--and most revered-- doctor in the world today. His role guiding America sanely and calmly through COVID ... earned him the trust of millions during one of the most terrifying periods in modern American history, but this was only the most recent of the global epidemics in which Dr. Fauci played a major role. His crucial role in researching HIV and bringing AIDS into sympathetic public view and his leadership in navigating the Ebola, SARS, West Nile, and anthrax crises, make him truly an American hero. His memoir reaches back to his boyhood in Brooklyn, New York, and carries through decades of caring for critically ill patients, navigating the whirlpools of Washington politics, and behind-the-scenes advising and negotiating with seven presidents on key issues from global AIDS relief to infectious disease preparedness at home"--

When it comes to Parkinson's disease, one of the most important issues revolves around early detection and accurate diagnosis. The intricacies of this neurodegenerative disorder often elude timely identification, leaving patients and healthcare providers grappling with its progressive symptoms. Ethical concerns surrounding the use of machine learning to aid in diagnosis further complicate this challenge. This issue is particularly significant for research scholars, PhD fellows, post-doc fellows, and medical and biomedical scholars seeking to unravel the mysteries of Parkinson's disease and develop more effective treatments. Intelligent Technologies and Parkinson's Disease: Prediction and Diagnosis serves as a beacon of hope in the quest to revolutionize Parkinson's disease diagnosis and treatment. It unveils the remarkable potential of artificial intelligence (AI) and machine learning (ML) in remodeling the way we approach this debilitating condition. With a comprehensive exploration of AI's capacity to analyze speech patterns, brain imaging data, and gait patterns, this book offers a powerful solution to the challenges of early detection and accurate diagnosis.

"Smart Business Problems and Analytical Hints in Cancer Research" is a pioneering exploration of the intersection between data science, artificial intelligence, machine learning, and oncology. Delving into 25 advanced questions derived from real-world cancer research scenarios, this book offers comprehensive guidelines on leveraging data-driven methodologies to address key challenges in the field. From genomic profiling and patient data integration to tumor heterogeneity analysis and immunotherapy optimization, each question presents a nuanced case study accompanied by practical solutions. Through integrative analysis and predictive modeling, readers gain insights into personalized treatment strategies, biomarker discovery, and therapeutic response prediction. With a focus on innovation and impact, this book equips researchers, clinicians, and data scientists with the tools and techniques necessary to navigate the complex landscape of cancer analytics. By harnessing the power of data science and AI, "Smart Business Problems and Analytical Hints in Cancer Research" promises to revolutionize the future of oncology and improve patient outcomes worldwide.

Pregnancy complicated by preexisting diabetes can be managed through expert protocols and patient partnerships. Based on the new American Diabetes Association recommendations, this revised edition widely expands on the fourth edition. Topics include: pre-pregnancy counseling, contraception, psychological impact, morning sickness, nutritional management, insulin, diagnostic testing and surveillance, gestational diabetes, neonatal care of infants, and postpartum follow-up.

On The Pathology Of Bronchitis, Catarrhal Pneumonia, Tubercle, And Allied Lesions Of The Human Lung is a medical book written by David James Hamilton and published in 1883. The book focuses on the pathology of various lung diseases such as bronchitis, catarrhal pneumonia, tuberculosis, and other related lesions. The author provides a detailed analysis of the causes, symptoms, and treatment of these respiratory diseases. The book is intended for medical professionals and students who are interested in studying the human lung and its various diseases. It is a valuable resource for understanding the pathology of lung diseases and their impact on the human body. The book is written in a clear and concise language, making it easy to understand and follow. It is an important contribution to the field of respiratory medicine and remains relevant to this day.This scarce antiquarian book is a facsimile reprint of the old original and may contain some imperfections such as library marks and notations. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions, that are true to their original work.

Diseases of the Heart and Thoracic Aorta is a comprehensive medical textbook written by Dr. Byrom Bramwell. The book provides a detailed overview of various heart diseases and disorders affecting the thoracic aorta. It covers a wide range of topics including the anatomy and physiology of the heart and thoracic aorta, the pathophysiology of heart diseases, diagnostic techniques, and treatment options. The book also includes chapters on specific heart conditions such as myocardial infarction, angina pectoris, and valvular heart disease. Additionally, it covers aortic aneurysms, aortic dissection, and other disorders affecting the thoracic aorta. The book is intended for medical professionals, including cardiologists, cardiac surgeons, and other healthcare providers involved in the care of patients with heart and thoracic aortic diseases. It is a valuable resource for students and researchers in the field of cardiology as well. Overall, Diseases of the Heart and Thoracic Aorta is a comprehensive reference book that provides a thorough understanding of heart and thoracic aortic diseases for medical professionals and students alike.This scarce antiquarian book is a facsimile reprint of the old original and may contain some imperfections such as library marks and notations. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions, that are true to their original work.

La moria grandissima began its terrible journey across the European and Asian continents in 1347, leaving unimaginable devastation in its wake. Five years later, twenty-five million people were dead, felled by the scourge that would come to be called the Black Death. The Great Mortality is the extraordinary epic account of the worst natural disaster in European history -- a drama of courage, cowardice, misery, madness, and sacrifice that brilliantly illuminates humankind's darkest days when an old world ended and a new world was born.

This book presents a comprehensive set of methods for quantifying geometric quantities such as the volume of a tumor, the total surface area of the alveoli in a lung, the length of plant roots, or of blood vessels, the number of neurons in a brain compartment, the connectivity number of trabecular bone, the mean size of grains in a rock, etc.. The methods, illustrated by twenty solved case studies, are based on properly sampled slices, sections, or projections of the material, observable under light, laser, or electron microscopy, or under non-invasive radiological devices such as ecography, computed tomography, or magnetic resonance imaging. Thus, the input usually consists of flat images, and the output consists of relevant quantities defined in three dimensions. Stereology is the discipline of providing sampling designs which warrant unbiased estimation of the corresponding quantities, that is, estimation with zero mean deviation from the target. Sampling is usually systematic (i.e., with regularly spaced probes), and sparse (as opposed to reconstructions) and it is thereby efficient and easy to implement.Stereology is essentially geometric sampling, grounded on integral geometry. The necessary elements of both disciplines are detailed in textbook style, and may be used for postgraduate courses, or to serve the interest of scientists in general. Hitherto no other book on stereology has appeared which encompasses the theory, methodology, and applications of stereology in an interconnected and comprehensive way. The currently available error variance prediction formulae under systematic sampling, and their (non-obvious) derivation, are all gathered, for the first time, in the last chapter. The exposition is augmented by 127 line drawings for the theory, and 27 color pictures of real materials for the case studies.

"Reclaim Your Health: Cancer" is a valuable handbook on this important medical topic award-winning author, Dr. Harris Phillip. Cancer occurs when our body mechanisms to take care of our cells fail on a number of levels. Loss of control over cell growth leads to different types of cancer. In this book, Dr. Phillip describes how our bodies can develop tumours and what preventive measures are possible to reduce the onset of this deadly disease. It offers excellent advice for both medical and non-medical readers.

El libro define una infección nosocomial, cómo se transmiten, tipos de infecciones que las causan, cómo prevenirlas y los principales agentes causales que las producen, ya sean bacterias, virus u hongos.

¿Biomedical Application of 4-Hexylresorcinol¿ is a comprehensive review of the latest research findings on the biomedical effects of 4-hexylresorcinol (4HR), a compound widely used as an antiseptic and food additive to prevent melanosis. Over the past two decades, the author has conducted extensive studies on 4HR, uncovering additional properties and applications that extend far beyond its traditional uses. This book aims to provide a thorough understanding of 4HR¿s numerous mechanisms and potential applications, with a focus on its anti-cancer, anti-inflammatory, and antioxidant effects.The book, ¿Biomedical Application of 4-Hexylresorcinol,¿ is poised to fill this critical knowledge gap. It will captivate professionals in the realms of biomedical research, medicine, and pharmacology, as well as students pursuing these disciplines. What truly sets our book apart is its unique concentration on 4HR and the wide-ranging applications in biomedical research and clinical practice. As interest in alternative therapeutic approaches continues to grow, along with the increasing acknowledgment of the value of natural compounds, this book is perfectly positioned to become an indispensable resource for researchers, clinicians, and aspiring professionals alike.

This book has expanded classic concept of immunology. Immunoglobulins have been widely discovered to be produced by many non-B cells. The non B cell-derived Igs display multifunction, which not only includes antibody activities and cellular biological functions under physiological conditions, but also directly participate in the pathological process of malignant tumour and immune-related diseases. This book provides new perspectives and a solid foundation for medical students, basic and clinical scientists to re-understand and broaden the physiological and pathological significance of Ig.

'I thought if I was going to die I should write some things down' Kirsty Everett was going to be an Olympic gymnast. But as she made plans to win gold, life, as it does, laughed at the goal she'd set. Aged nine, she was diagnosed with leukaemia and spent the next two and a half years in treatment and attending the funerals of children she met in the cancer ward. At the age of sixteen, Kirsty's cancer returned. Faced with a devastating prognosis, she threw herself into as much as she could - friends, school, drama, sport, even a life-writing course with Patti Miller. As she said, 'I thought if I was going to die I should write some things down.'Against the odds, Kirsty survived. She never achieved gold at the Olympics, but she learned a lot about people, attitudes and resilience. This is a book about growing up different when you want to be the same; sparking hostility where there should be support; and how love can be tested to its utmost. It's wise and unflinching and hopeful, and you won't feel the same after reading it.PRAISE'Told by a writer who's a real natural' Steven Carroll, Sydney Morning Herald'[An] incredible book ... I haven't been able to stop thinking about Kirsty's journey' Chyka Keebaugh'Everett is a born writer, her compelling story shot through with the extraordinary sensitivities of childhood' - B+P magazine'Honey Blood is one of the most exuberant, life-affirming memoirs I have ever read. The fact that it is about the uncompromising reality of childhood cancer, makes it all the more extraordinary. Read it and be utterly bowled over Kirsty Everett's astonishing courage, honesty and cheeky humour' - Patti Miller, author'If the Olympic Games are designed around people achieving their personal best, commitment, courage, determination and reaching their goals, Kirsty has been to the equivalent of two Olympics' - Wayne Staunton, managing director, Sold Out events management'Do not be afraid of this book. The big C in it is not cancer, it's Courage. The courage to deal with pain, loss, fear and the shattering of a young girl's big dreams.'Instead of tiptoeing around the tough stuff, and leaving the most difficult bits out, Kirsty Everett dives right in, taking the reader into her world, bravely, honestly, with raw humour and grit. We get up close to her tight-knit family, boisterous friends, tender first loves, doctors both brusque and kind, and rude strangers. Death hovers on every page, but life's vitality and Kirsty's defiant spirit shove it aside.'This refreshingly straight-talking account of adolescent leukaemia goes beyond pain to a fuller, wiser, deeper understanding of what really matters when everything you hope for hangs by a thread. It offers the best medicine for anyone who has ever faced relentless physical and mental odds and obstacles that create seemingly insurmountable roadblocks as tests of character. It may not be a cure, but it is one mighty transfusion of the powerful drugs that make us human and help us survive: hope, compassion, and love' - Caroline Baum, author'This is a coming of age story that will shock and inspire you. Told with searing honesty Honey Blood tells the close-up story of growing up while everything is falling down. In her compassionate, funny and warm way Kirsty Everett tells her story that will inspire others to tell and live through their stories. A wonderful and truthful insight into how to survive and thrive against the odds' - Michael Anderson, Professor of Creativity and Arts Education, University of Sydney

Nanophototherapy: Preparations and Applications provides a comprehensive overview of the various multifunctional nanoparticles used for phototherapy, with an emphasis on fundamental nanotechnology and the latest research of photothermal therapy (PTT) and photodynamic therapy (PDT). The different types of phototherapeutic nanomaterials are thoroughly described, along with their structural features and synthesis. This is the first book to cover nanomaterial-based phototherapy for both cancer and bacterial infections. It is an essential resource for researchers, academics, and professionals interested in the potential of multifunctional nanomaterials for therapeutic applications.

This book presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases, including diabetes, cancer, cardiovascular disease, and bone regeneration. The authors first cover the fundamentals of conventional immunology and immunomodulation, before focusing on the history, advantages, and challenges of cell therapies. Biological cell therapy has gained immense attention for various diseases due to unique advantages it has over chemical drugs regarding cost, ease of production, toxicity, and therapeutic efficacy. However, these cell-based therapies need an inert delivery system that can locally deliver cells and minimally elicit foreign body response. The book discusses the foreign body response to the immunomodulatory biomaterials as well as the current and future strategies for potential mitigation of considerable immune responses toward immunomodulatory biomaterials and devices.

A primer about hundreds of infections, The Hidden Zoo Inside You provides the foundations of infectious disease required to understand pandemics through the use of humor, drawings, and even doodles. The entire book is handwritten and includes diagrams and sketches that explain, in layman's terms, the origin, epidemiology, clinical features, public health concerns of various life-threatening diseases. It reveals to the reader how the microbial world coexists with the rest of the Animal Kingdom and even the Plant Kingdom. The diseases elucidated in the book include the plague, smallpox, influenza, COVID, and a host of others. The book provides contextual information and the disaster management required for each disease presented within its pages.Described as "a graphic novel like Maus meeting Gray's Anatomy," the content of the book is broad and detailed, written in language (and drawings) that everyone can understand, and covers topics like the initiation and course of various pandemics across history, for example, the Black Death in England in the 1300s, the Plague of Athens (typhus) in 430 BC, the Ebola endemic in Africa that began in 1976 and continues to this day, the Antonine Plague (smallpox) that decimated Rome between 165 and 180 AD, and¿of course¿the COVID pandemic that began in Wuhan, China at the end of 2019. Other features of the book include explanations of how to choose the right mask for the job by explaining the distinction between droplets and aerosols, a guide on how to easily memorize information, an extensive index that will help the reader find specific information in the book, and a massive online bibliography that summarizes and provides more context and information about the sources of information. The book and bibliography are rich in information that will create common ground between health professionals, educators, students, parents, and politicians.