Drug Metabolism and Pharmacokinetics - Erica Helmer - Bog

Drug metabolism refers to the conversion of a drug molecule into other related compounds throughout the body. There are drug modifying enzymes (DME), such as cytochrome P450, which are involved in the modification of an administered drug during the process of drug metabolism. The liver is the primary organ involved in the modification and removal of drug compounds, along with numerous other locations within the body. The therapeutic efficacy of a drug is influenced by many factors, including pharmacokinetics. It refers to the passage of a drug through the body's biological system. There are four different phases in the passage of a drug in the human body, which includes absorption, distribution, metabolism, and excretion (ADME). These pharmacokinetic qualities collectively provide deeper insights into the performance of a drug and help to establish the optimal dosage. This book provides significant information to help develop a good understanding of drug metabolism and pharmacokinetics. It presents researches and studies performed by experts across the globe. This book aims to equip students and experts with the advanced topics and upcoming concepts in this area of study.