Study of the quality parameters of atenolol tablets - Raúl Alejandro Jiménez Cevallos - Bog

The pharmaceutical market today has generated a wide variety of drugs, including innovative and generic medicines, which are controversial because they differ in cost, efficacy and effectiveness. Generic drugs contain the same active ingredient in the same concentration according to official specifications, yet there are laboratories that do not meet high quality standards, resulting in the production and consumption of drugs with little or no therapeutic activity. In the present study, quality control tests were carried out on Atenolol 50 mg tablets produced by two pharmaceutical companies and marketed in the city of Guayaquil, and a comparison was made with the reference medicine. The results showed that there are significant differences in some quality parameters and finally the generic drugs are not therapeutically bioequivalent to the reference drug.